heart development

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1ADM-CALCRL+GPER1+RAMP3ADML_HUMAN - Ligand-ReceptorSignaling by Adrenomedullin
2APELA-APLNRELA_HUMAN - APJ_HUMANLigand-ReceptorSignaling by Apelin
3BMP2-ACVR2B+BMPR1ABMP2_HUMAN - Ligand-ReceptorSignaling by BMP
4BMP2-ACVR2B+BMPR1BBMP2_HUMAN - Ligand-ReceptorSignaling by BMP
5FN1-ITGA3+ITGB1FINC_HUMAN - Adhesion-AdhesionAdhesion by Fibronectin
6GJA1-GJA5CXA1_HUMAN - CXA5_HUMANGap-GapAdhesion by GAP junction
7OXT-OXTRNEU1_HUMAN - OXYR_HUMANLigand-ReceptorSignaling by Oxytocin
8RBP4-STRA6RET4_HUMAN - STRA6_HUMANLigand-Receptor
9TGFB1-ACVR1+TGFBR2TGFB1_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
10TGFB1-TGFBR1+TGFBR2TGFB1_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
11TGFB2-ACVR1+TGFBR2TGFB2_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
12TGFB2-TGFBR1+TGFBR2TGFB2_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
13WNT3A-WIF1WNT3A_HUMAN - WIF1_HUMANLigand-LigandSignaling by WNT inhibition

II. Literature review

[source]
Nameheart development
IDGO_0007507
collection_id

Biological process

Alternative ID

GO:0007511

Description

The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.

Related synonym

cardiac development

External URL
Genes
EIF4G2MEF2BCFC1KDM6BPDLIM4GJA5KDM6ADRC1ATMOXTRERBB2CC2D2ACASP8CRIP1CASP3PKP2SHHMEF2ACDKN1AFREM2HAND2ID3AKAP13SYPL2PCSK5WT1ODAD4ADAP2CCM2FOXF1IL1AMBTAFAZZINCACNA1CHAND1DNAAF3CACYBPPOPDC2FLRT3CRIPTO3CITED2SOX4NTRK3POU6F1TGFBR1KCNQ1ACVR2BIFT140FOXL1PDGFBCOL3A1PPP3R1KAT2AGJA1IFT25PDLIM2SH3PXD2BBICC1POU4F2ZDHHC16FGF12SRIAPELANCOA6POPDC3OXTACVRL1PTENFOXC1PPARASMYD2BORCS8MICAL2SALL1WNK1RAMP2ERBB3ID2UTYTBX1CASP7JMJD6CFC1BTNNI3CXADRTGFB1MAP2K5DNAAF4nkx2-5_humanDNAI1GYS1GNA11LDB3BMP2TGFB2MYL2POU4F1RBP4MTHFD1IRX4FOXJ1STRA6MMP2ITGA3FBN1ANKS6POFUT1ACVR1ALPK3ERBB4WIF1MAP2K1SMYD1HDAC9GLI3GLI2CADFN1PDLIM7THEP300TRAF3IP2TSC2MAP2K2DAW1RB1CC1PPP3CBTAB2TBX5SMYD4MTERF4FOXC2SOX9ODAD2MAP2K3SOX17LOXNOTCH1PTPN11ISL1MEF2CNKX2-5OSR1DVL1P1SMG9IFT74DZIP1SRFEEF1AKMT4-ECE2ECE1PRKDCPCNAMKKSPTPRJWDR11ZFPM2GRK2HEXIM1WNT3ANF1RIPPLY3ASCL1PDLIM1PDLIM3CRIPTOSOD2TGFBR2DNAH5PKD1EPORNEK8CDKN1BDVL2CALCRLMED12MOSPD3APLNRHEG1BCORTFDP2PSKH1ZFPM1PKD2NFATC4SHC1COL6A1PDLIM5MIXL1KAT2BNKX3-1ZFP36L1HSPB7BVESRBPJTCF25TEKADMAP1B1PRICKLE4TBC1D32