Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 13 studies | 34% ± 14% | |
astrocyte | 13 studies | 34% ± 17% | |
endothelial cell | 11 studies | 26% ± 10% | |
oligodendrocyte precursor cell | 10 studies | 36% ± 14% | |
glutamatergic neuron | 9 studies | 34% ± 17% | |
microglial cell | 9 studies | 30% ± 11% | |
fibroblast | 8 studies | 28% ± 13% | |
GABAergic neuron | 6 studies | 36% ± 18% | |
adipocyte | 6 studies | 24% ± 5% | |
macrophage | 5 studies | 30% ± 12% | |
Mueller cell | 4 studies | 26% ± 7% | |
amacrine cell | 4 studies | 27% ± 4% | |
retina horizontal cell | 4 studies | 30% ± 7% | |
retinal cone cell | 4 studies | 24% ± 6% | |
smooth muscle cell | 4 studies | 27% ± 9% | |
monocyte | 4 studies | 26% ± 9% | |
club cell | 4 studies | 34% ± 9% | |
pericyte | 4 studies | 23% ± 3% | |
interneuron | 4 studies | 36% ± 8% | |
B cell | 3 studies | 25% ± 3% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 19% ± 1% | |
GABAergic interneuron | 3 studies | 28% ± 10% | |
CD4-positive, alpha-beta T cell | 3 studies | 21% ± 3% | |
cardiac muscle cell | 3 studies | 31% ± 8% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 3 studies | 21% ± 3% | |
GABAergic amacrine cell | 3 studies | 26% ± 4% | |
glycinergic amacrine cell | 3 studies | 22% ± 1% | |
retinal ganglion cell | 3 studies | 28% ± 14% | |
retinal rod cell | 3 studies | 27% ± 8% | |
retinal pigment epithelial cell | 3 studies | 42% ± 21% | |
ependymal cell | 3 studies | 34% ± 6% | |
epithelial cell | 3 studies | 46% ± 13% | |
T cell | 3 studies | 22% ± 6% | |
alveolar macrophage | 3 studies | 28% ± 9% | |
ciliated cell | 3 studies | 28% ± 5% | |
natural killer cell | 3 studies | 19% ± 3% | |
type I pneumocyte | 3 studies | 30% ± 8% | |
type II pneumocyte | 3 studies | 32% ± 10% | |
basal cell | 3 studies | 38% ± 22% | |
goblet cell | 3 studies | 35% ± 24% | |
regulatory T cell | 3 studies | 19% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 1778.56 | 245 / 245 | 99% | 9.13 | 495 / 502 |
brain | 71% | 615.55 | 1884 / 2642 | 55% | 3.61 | 390 / 705 |
bladder | 67% | 1028.24 | 14 / 21 | 51% | 3.77 | 255 / 504 |
kidney | 78% | 913.28 | 69 / 89 | 37% | 2.68 | 335 / 901 |
esophagus | 66% | 911.51 | 952 / 1445 | 46% | 3.54 | 85 / 183 |
liver | 71% | 538.37 | 161 / 226 | 38% | 1.62 | 154 / 406 |
skin | 67% | 1251.62 | 1208 / 1809 | 42% | 3.08 | 199 / 472 |
lung | 68% | 1232.11 | 395 / 578 | 40% | 3.17 | 466 / 1155 |
pancreas | 63% | 618.06 | 207 / 328 | 45% | 2.71 | 80 / 178 |
intestine | 64% | 918.42 | 619 / 966 | 39% | 2.35 | 204 / 527 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.95 | 1 / 1 |
stomach | 64% | 734.82 | 228 / 359 | 35% | 2.28 | 99 / 286 |
thymus | 66% | 1291.69 | 434 / 653 | 29% | 2.74 | 178 / 605 |
adrenal gland | 61% | 1031.12 | 158 / 258 | 34% | 1.81 | 78 / 230 |
adipose | 68% | 1144.23 | 816 / 1204 | 0% | 0 | 0 / 0 |
muscle | 68% | 990.13 | 543 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 66% | 873.98 | 879 / 1335 | 0% | 0 | 0 / 0 |
breast | 63% | 1126.47 | 291 / 459 | 1% | 0.11 | 12 / 1118 |
tonsil | 0% | 0 | 0 / 0 | 64% | 6.46 | 29 / 45 |
heart | 64% | 549.84 | 554 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 64% | 978.92 | 596 / 929 | 0% | 0 | 0 / 0 |
spleen | 64% | 1078.78 | 154 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 38% | 2.75 | 11 / 29 |
eye | 0% | 0 | 0 / 0 | 26% | 1.44 | 21 / 80 |
uterus | 0% | 0 | 0 / 170 | 7% | 0.43 | 30 / 459 |
ovary | 1% | 1.52 | 1 / 180 | 0% | 0 | 0 / 430 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0010468 | Biological process | regulation of gene expression |
GO_0006338 | Biological process | chromatin remodeling |
GO_0007507 | Biological process | heart development |
GO_0005654 | Cellular component | nucleoplasm |
GO_0044666 | Cellular component | MLL3/4 complex |
GO_0031490 | Molecular function | chromatin DNA binding |
GO_0032452 | Molecular function | histone demethylase activity |
GO_0071558 | Molecular function | histone H3K27me2/H3K27me3 demethylase activity |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | UTY |
Protein name | [histone H3]-trimethyl-L-lysine(27) demethylase (EC 1.14.11.68) UTY protein Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 227 UTY Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 193 Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 155 Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 142 Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 225 Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 276 Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 226 Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 154 Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 71 Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 117 Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 100 (Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 116) (Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 120) (Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 266) Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 72 Ubiquitously transcribed tetratricopeptide repeat Y-linked isoform 3 Histone demethylase UTY (EC 1.14.11.68) (Ubiquitously-transcribed TPR protein on the Y chromosome) (Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase UTY) Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 86 |
Synonyms | KDM6C |
Description | FUNCTION: Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity. . |
Accessions | ENST00000624098.3 [O14607-5] F4MHE1 E1NZ94 F4MH55 F4MH40 F4MHG9 F4MHQ1 F4MH30 F4MHC9 F4MHI3 F4MHI5 E1NZ86 F4MHR2 A0A804HKG5 F4MHK5 F4MHM4 F4MH61 F4MHJ7 F4MHS7 F4MHL7 F4MHP6 F4MHG5 F4MHI1 F4MHR9 F4MHJ6 F4MHP0 F4MHG7 F4MHE0 F4MHK7 F4MHL1 F4MHA3 E1U1M9 F4MHN2 F4MHP2 F4MHF7 F4MHH5 Q9NR08 ENST00000682913.1 [O14607-4] ENST00000382896.9 F4MH57 F4MH90 F4MH75 F4MHM1 A0A8C8KHL4 ENST00000682761.1 A0A804HL26 F4MHD7 E1U1N1 F4MHH0 F4MHR7 F4MHF8 F4MHQ0 F4MHB3 E1NZ84 F4MH66 F4MHK2 E1NZ93 F4MH44 F4MHS2 F5H3N7 F4MHE6 F4MHH2 F4MHN5 F4MH62 F4MHA7 F4MH82 F4MH92 ENST00000684226.1 F4MH69 E1U198 F4MH89 E1U1M3 F4MHF0 F4MHI8 C3UJR9 F4MHE9 F4MHG4 E1U1N0 F4MHK0 E1NZA0 F4MHJ8 F4MHB5 A6NCS7 F4MHQ2 F4MHI4 F5GWV3 F4MHM8 F4MHN4 F4MHN1 F4MHQ7 F4MHH8 F4MHP1 E1NZ92 F4MHB6 F4MH27 ENST00000538878.6 F4MHF6 F4MH88 F4MHR0 F4MHD8 Q6IPS8 F4MH77 F4MHS0 ENST00000362096.8 [O14607-3] F4MH94 F4MHQ5 F4MH81 E1U0S4 O14607 A0A804HHT1 E1U1M5 F4MH28 F4MHL4 Q590G7 F4MHM2 F4MHP3 F4MHG8 F4MHJ1 F4MHS1 F4MHD2 F4MHK8 ENST00000329134.9 [O14607-2] F4MHI6 F4MHD4 E1NZ90 F4MHC1 F4MHN6 F4MHH4 F4MH41 E1U1M7 F4MH47 F4MH64 F4MHR6 F4MHJ0 F4MH39 F4MH36 F4MH99 A0A804HI49 F4MHL2 F4MHD9 F5H8B4 F4MHD1 F4MH86 F4MHI7 F4MH56 F4MHM6 E1NZ85 F4MH63 F4MHG1 F4MHG3 ENST00000682112.1 Q86UB8 F4MH51 E1NZ99 F4MHH9 F4MH46 F4MH60 F4MHK1 Q9P108 F4MHL5 F4MHD5 F4MH32 F4MHP5 F4MHE7 F4MHJ4 F4MHS3 ENST00000617789.5 F4MH52 F4MH31 F4MHB8 F4MH59 F4MHR5 F4MHS6 ENST00000618474.5 F4MHC6 F4MHM9 ENST00000612274.5 E1NZ82 E1NZ88 F4MH97 E1U1M2 F4MHB7 F4MH91 F4MHI9 A0A087X0Y2 F4MHL6 F4MHP7 E1NZ91 F4MHG0 F4MHG2 F4MHE5 F4MHB9 F4MHB2 F4MH34 E1U1M8 E1NZ97 F4MHC7 F4MHA8 F4MHC2 F4MHF2 ENST00000682216.1 F4MHA0 F4MHE4 E1NZ89 F4MHC8 A0A087X2I9 F4MHG6 F4MHJ2 F4MHR8 F4MHD0 F4MHK9 F4MH33 F4MH43 ENST00000478900.5 F4MHA5 F4MH78 ENST00000540140.6 A0A804HJV1 F4MH53 F4MH87 F4MHS4 F4MHJ3 F4MHP9 E1U1M4 F4MH84 E1NZ87 F4MH49 F4MH70 F4MHP8 F4MH54 F4MHI0 F4MHF1 F4MH74 E1NZ79 ENST00000545955.6 F4MH93 F4MHL9 F4MHH3 F4MH45 F4MHH6 F4MHD3 F4MHA6 E1NZ95 F4MH42 F4MHD6 F4MH73 F4MHS5 F4MHA9 F4MHJ9 F4MHB1 F4MH65 F4MH67 F4MH79 F4MHK4 F4MHE8 F4MHC4 A0A096LPD8 ENST00000537580.6 E1NZ98 F4MHM0 F4MHN7 F4MHR1 E1NZ81 ENST00000331397.8 [O14607-1] E1U1M6 F4MHM3 E1NZ96 F4MH68 F4MHI2 F4MH83 F4MHQ3 F4MH58 F4MHL8 F4MH37 F4MHC0 F4MHM5 A0A087X248 F4MHR4 F4MH35 F4MHA2 ENST00000382893.2 F4MH50 F4MH98 F4MHA4 F4MH38 F4MHH1 F4MH29 F4MHH7 F4MH48 |