Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 20 studies | 70% ± 19% | |
| deuterosomal cell | 4 studies | 26% ± 9% | |
| club cell | 4 studies | 32% ± 13% | |
| type II pneumocyte | 4 studies | 18% ± 1% | |
| epithelial cell | 3 studies | 30% ± 5% | |
| ependymal cell | 3 studies | 49% ± 11% | |
| respiratory goblet cell | 3 studies | 28% ± 10% |
Insufficient scRNA-seq data for expression of DNAH5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 98% | 970.47 | 239 / 245 | 97% | 10.58 | 485 / 502 |
| lung | 97% | 1517.14 | 562 / 578 | 65% | 4.25 | 748 / 1155 |
| pancreas | 95% | 513.23 | 311 / 328 | 62% | 1.52 | 111 / 178 |
| kidney | 99% | 431.72 | 88 / 89 | 52% | 1.94 | 473 / 901 |
| breast | 67% | 562.49 | 308 / 459 | 75% | 4.51 | 842 / 1118 |
| thymus | 98% | 623.63 | 642 / 653 | 19% | 0.37 | 113 / 605 |
| brain | 89% | 224.95 | 2352 / 2642 | 23% | 0.58 | 164 / 705 |
| stomach | 90% | 323.52 | 324 / 359 | 11% | 0.39 | 32 / 286 |
| liver | 75% | 481.12 | 169 / 226 | 23% | 0.78 | 94 / 406 |
| esophagus | 51% | 76.80 | 743 / 1445 | 34% | 1.06 | 63 / 183 |
| intestine | 60% | 78.53 | 577 / 966 | 14% | 0.31 | 75 / 527 |
| bladder | 48% | 121.38 | 10 / 21 | 25% | 0.91 | 125 / 504 |
| adrenal gland | 26% | 30.93 | 66 / 258 | 33% | 0.69 | 77 / 230 |
| skin | 50% | 65.15 | 911 / 1809 | 3% | 0.62 | 15 / 472 |
| uterus | 22% | 134.78 | 38 / 170 | 25% | 0.75 | 117 / 459 |
| ovary | 4% | 5.41 | 7 / 180 | 25% | 0.51 | 109 / 430 |
| spleen | 27% | 26.62 | 64 / 241 | 0% | 0 | 0 / 0 |
| adipose | 23% | 21.55 | 281 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 20% | 0.46 | 9 / 45 |
| blood vessel | 12% | 10.51 | 161 / 1335 | 0% | 0 | 0 / 0 |
| heart | 3% | 2.21 | 25 / 861 | 0% | 0 | 0 / 0 |
| muscle | 1% | 0.73 | 8 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 1.10 | 2 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0060271 | Biological process | cilium assembly |
| GO_0007507 | Biological process | heart development |
| GO_0007368 | Biological process | determination of left/right symmetry |
| GO_0051649 | Biological process | establishment of localization in cell |
| GO_0003351 | Biological process | epithelial cilium movement involved in extracellular fluid movement |
| GO_0030317 | Biological process | flagellated sperm motility |
| GO_0021670 | Biological process | lateral ventricle development |
| GO_0003341 | Biological process | cilium movement |
| GO_0060294 | Biological process | cilium movement involved in cell motility |
| GO_0036158 | Biological process | outer dynein arm assembly |
| GO_0005576 | Cellular component | extracellular region |
| GO_0097729 | Cellular component | 9+2 motile cilium |
| GO_0005874 | Cellular component | microtubule |
| GO_0097728 | Cellular component | 9+0 motile cilium |
| GO_0031514 | Cellular component | motile cilium |
| GO_0005930 | Cellular component | axoneme |
| GO_0036157 | Cellular component | outer dynein arm |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005524 | Molecular function | ATP binding |
| GO_0051959 | Molecular function | dynein light intermediate chain binding |
| GO_0008569 | Molecular function | minus-end-directed microtubule motor activity |
| GO_0045505 | Molecular function | dynein intermediate chain binding |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| Gene name | DNAH5 |
| Protein name | Dynein axonemal heavy chain 5 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Axonemal dynein, heavy chain |
| Synonyms | DNAHC5 HL1 KIAA1603 |
| Description | FUNCTION: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles. |
| Accessions | O95496 ENST00000265104.5 A0A7P0Z455 Q8TE73 ENST00000681290.1 |
