Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 16 studies | 40% ± 15% | |
fibroblast | 13 studies | 33% ± 10% | |
macrophage | 9 studies | 32% ± 10% | |
oligodendrocyte | 9 studies | 32% ± 11% | |
endothelial cell | 6 studies | 26% ± 13% | |
oligodendrocyte precursor cell | 5 studies | 25% ± 9% | |
myeloid cell | 5 studies | 31% ± 8% | |
epithelial cell | 4 studies | 26% ± 4% | |
GABAergic neuron | 4 studies | 28% ± 7% | |
glutamatergic neuron | 4 studies | 28% ± 11% | |
endothelial cell of lymphatic vessel | 4 studies | 26% ± 7% | |
smooth muscle cell | 4 studies | 21% ± 4% | |
microglial cell | 3 studies | 31% ± 11% | |
neuron | 3 studies | 32% ± 8% | |
dendritic cell | 3 studies | 19% ± 0% | |
Mueller cell | 3 studies | 29% ± 12% | |
abnormal cell | 3 studies | 19% ± 3% | |
connective tissue cell | 3 studies | 29% ± 16% | |
ependymal cell | 3 studies | 42% ± 13% | |
alveolar macrophage | 3 studies | 46% ± 2% | |
monocyte | 3 studies | 26% ± 6% | |
myofibroblast cell | 3 studies | 26% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 5775.65 | 1441 / 1445 | 100% | 40.03 | 183 / 183 |
breast | 100% | 7389.58 | 458 / 459 | 99% | 42.48 | 1106 / 1118 |
skin | 100% | 6488.28 | 1809 / 1809 | 98% | 41.56 | 461 / 472 |
uterus | 100% | 9171.06 | 170 / 170 | 97% | 30.90 | 447 / 459 |
lung | 100% | 6533.62 | 578 / 578 | 97% | 29.93 | 1124 / 1155 |
intestine | 100% | 4657.78 | 963 / 966 | 97% | 25.16 | 512 / 527 |
ovary | 100% | 6746.36 | 180 / 180 | 96% | 24.40 | 411 / 430 |
stomach | 94% | 4067.97 | 339 / 359 | 98% | 26.68 | 281 / 286 |
bladder | 100% | 6977.48 | 21 / 21 | 92% | 22.03 | 464 / 504 |
thymus | 99% | 3081.53 | 644 / 653 | 93% | 16.15 | 564 / 605 |
pancreas | 90% | 1839.09 | 295 / 328 | 98% | 37.64 | 174 / 178 |
adrenal gland | 100% | 7590.60 | 258 / 258 | 85% | 21.83 | 196 / 230 |
brain | 84% | 1818.36 | 2207 / 2642 | 99% | 37.40 | 701 / 705 |
prostate | 100% | 4992.55 | 244 / 245 | 77% | 9.93 | 385 / 502 |
adipose | 100% | 7570.89 | 1204 / 1204 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.82 | 1 / 1 |
blood vessel | 100% | 4923.71 | 1334 / 1335 | 0% | 0 | 0 / 0 |
kidney | 26% | 458.58 | 23 / 89 | 71% | 13.49 | 642 / 901 |
tonsil | 0% | 0 | 0 / 0 | 93% | 31.81 | 42 / 45 |
eye | 0% | 0 | 0 / 0 | 90% | 16.71 | 72 / 80 |
heart | 72% | 1422.85 | 619 / 861 | 0% | 0 | 0 / 0 |
spleen | 71% | 1864.60 | 170 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 59% | 9.28 | 17 / 29 |
liver | 7% | 97.82 | 15 / 226 | 31% | 4.76 | 127 / 406 |
muscle | 28% | 430.69 | 225 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 20% | 324.86 | 187 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007507 | Biological process | heart development |
GO_0042554 | Biological process | superoxide anion generation |
GO_0022617 | Biological process | extracellular matrix disassembly |
GO_0001654 | Biological process | eye development |
GO_0071800 | Biological process | podosome assembly |
GO_0030154 | Biological process | cell differentiation |
GO_0060612 | Biological process | adipose tissue development |
GO_0001501 | Biological process | skeletal system development |
GO_0006801 | Biological process | superoxide metabolic process |
GO_0060348 | Biological process | bone development |
GO_0072657 | Biological process | protein localization to membrane |
GO_0002102 | Cellular component | podosome |
GO_0070161 | Cellular component | anchoring junction |
GO_0005737 | Cellular component | cytoplasm |
GO_0042995 | Cellular component | cell projection |
GO_0032266 | Molecular function | phosphatidylinositol-3-phosphate binding |
GO_0016176 | Molecular function | superoxide-generating NADPH oxidase activator activity |
GO_0042169 | Molecular function | SH2 domain binding |
GO_0080025 | Molecular function | phosphatidylinositol-3,5-bisphosphate binding |
GO_0005515 | Molecular function | protein binding |
GO_0010314 | Molecular function | phosphatidylinositol-5-phosphate binding |
Gene name | SH3PXD2B |
Protein name | Alternative protein SH3PXD2B SH3 and PX domains 2B SH3 and PX domain-containing protein 2B (Adapter protein HOFI) (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains) |
Synonyms | hCG_40282 KIAA1295 FAD49 TKS4 |
Description | FUNCTION: Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation (By similarity). . |
Accessions | ENST00000519643.5 G3V144 A1X283 ENST00000311601.6 A0A1B0GUF2 L8EC68 ENST00000636523.1 H0YAU1 ENST00000518522.5 |