Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| cardiac muscle cell | 6 studies | 45% ± 14% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| heart | 4 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| muscle | 100% | 28885.09 | 803 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 15757.85 | 835 / 861 | 0% | 0 | 0 / 0 |
| intestine | 64% | 2293.07 | 621 / 966 | 5% | 0.18 | 25 / 527 |
| stomach | 36% | 1476.22 | 128 / 359 | 15% | 1.94 | 42 / 286 |
| esophagus | 40% | 640.03 | 574 / 1445 | 4% | 0.06 | 7 / 183 |
| breast | 12% | 163.75 | 57 / 459 | 17% | 0.81 | 190 / 1118 |
| prostate | 5% | 92.84 | 12 / 245 | 7% | 0.99 | 34 / 502 |
| tonsil | 0% | 0 | 0 / 0 | 9% | 0.72 | 4 / 45 |
| brain | 0% | 0.38 | 1 / 2642 | 8% | 0.25 | 56 / 705 |
| skin | 0% | 10.31 | 3 / 1809 | 6% | 0.12 | 29 / 472 |
| uterus | 0% | 0 | 0 / 170 | 5% | 5.10 | 25 / 459 |
| lung | 0% | 9.30 | 1 / 578 | 5% | 1.29 | 53 / 1155 |
| pancreas | 0% | 0 | 0 / 328 | 4% | 1.08 | 8 / 178 |
| bladder | 0% | 0 | 0 / 21 | 3% | 0.06 | 13 / 504 |
| liver | 0% | 0 | 0 / 226 | 2% | 0.09 | 8 / 406 |
| thymus | 1% | 9.99 | 4 / 653 | 1% | 0.06 | 5 / 605 |
| blood vessel | 1% | 59.04 | 19 / 1335 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 180 | 1% | 0.04 | 5 / 430 |
| peripheral blood | 0% | 4.27 | 4 / 929 | 0% | 0 | 0 / 0 |
| adipose | 0% | 3.25 | 5 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 3.38 | 1 / 258 | 0% | 0 | 0 / 230 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0 | 0 / 901 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006338 | Biological process | chromatin remodeling |
| GO_0045663 | Biological process | positive regulation of myoblast differentiation |
| GO_0035914 | Biological process | skeletal muscle cell differentiation |
| GO_0032259 | Biological process | methylation |
| GO_0010831 | Biological process | positive regulation of myotube differentiation |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0007507 | Biological process | heart development |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0140999 | Molecular function | histone H3K4 trimethyltransferase activity |
| GO_0003677 | Molecular function | DNA binding |
| GO_0003714 | Molecular function | transcription corepressor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | SMYD1 |
| Protein name | [histone H3]-lysine(4) N-trimethyltransferase (EC 2.1.1.354) Histone-lysine N-methyltransferase SMYD1 (EC 2.1.1.354) (SET and MYND domain-containing protein 1) |
| Synonyms | |
| Description | FUNCTION: Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis. . |
| Accessions | ENST00000438570.1 Q5GJ33 C9JUP3 ENST00000419482.7 Q8NB12 E9PHG3 ENST00000444564.2 |