histone H3K4 trimethyltransferase activity

I. Literature review

[source]
Namehistone H3K4 trimethyltransferase activity
IDGO_0140999
collection_id

Molecular function

Exact synonym

histone H3K4 trimethylase activity, histone lysine N-trimethyltransferase activity (H3-K4 specific)

Description

Catalysis of the reaction: L-lysyl4-[histone H3] + 3 S-adenosyl-L-methionine = 2 H+ + N6,N6-trimethyl-L-lysyl4-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 4 of histone H3, producing histone H3K4me3.

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Genes