IRX4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of IRX4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of IRX4 at tissue level.

III. Associated gene sets

GO_0030182Biological processneuron differentiation
GO_0048561Biological processestablishment of animal organ orientation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0048468Biological processcell development
GO_0007507Biological processheart development
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameIRX4
Protein nameIroquois homeobox 4
Iroquois-class homeodomain protein IRX-4 (Homeodomain protein IRXA3) (Iroquois homeobox protein 4)
SynonymsIRXA3
DescriptionFUNCTION: Likely to be an important mediator of ventricular differentiation during cardiac development.

AccessionsENST00000513692.5 [P78413-1]
P78413
ENST00000508261.5
ENST00000231357.7 [P78413-1]
D6RC00
ENST00000505790.5 [P78413-1]
D6RAS8
ENST00000613726.4 [P78413-2]
ENST00000622814.4 [P78413-2]
ENST00000511126.1