Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 49 studies | 46% ± 18% | |
endothelial cell of lymphatic vessel | 23 studies | 51% ± 16% | |
capillary endothelial cell | 16 studies | 49% ± 18% | |
vein endothelial cell | 16 studies | 67% ± 19% | |
endothelial cell of artery | 14 studies | 59% ± 24% | |
endothelial cell of vascular tree | 14 studies | 48% ± 13% | |
oligodendrocyte precursor cell | 13 studies | 40% ± 20% | |
adipocyte | 9 studies | 45% ± 13% | |
smooth muscle cell | 6 studies | 22% ± 7% | |
pericyte | 6 studies | 33% ± 23% | |
fibroblast | 5 studies | 30% ± 7% | |
endothelial cell of sinusoid | 4 studies | 38% ± 17% | |
glomerular endothelial cell | 4 studies | 55% ± 6% | |
astrocyte | 3 studies | 24% ± 6% | |
endocardial cell | 3 studies | 69% ± 6% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
adipose | 3 studies | 26% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 10434.90 | 578 / 578 | 89% | 15.50 | 1030 / 1155 |
breast | 99% | 3939.61 | 456 / 459 | 88% | 16.41 | 982 / 1118 |
thymus | 100% | 3901.56 | 653 / 653 | 85% | 22.65 | 517 / 605 |
esophagus | 93% | 1131.96 | 1337 / 1445 | 87% | 13.86 | 160 / 183 |
kidney | 90% | 1047.16 | 80 / 89 | 80% | 40.01 | 719 / 901 |
adrenal gland | 87% | 955.81 | 225 / 258 | 68% | 10.55 | 156 / 230 |
prostate | 88% | 1151.50 | 215 / 245 | 67% | 7.87 | 335 / 502 |
brain | 48% | 347.95 | 1258 / 2642 | 95% | 53.01 | 671 / 705 |
uterus | 99% | 2174.21 | 168 / 170 | 43% | 5.40 | 198 / 459 |
stomach | 69% | 740.23 | 249 / 359 | 67% | 9.92 | 192 / 286 |
ovary | 99% | 1550.99 | 179 / 180 | 33% | 3.06 | 140 / 430 |
intestine | 81% | 997.77 | 787 / 966 | 50% | 6.10 | 266 / 527 |
bladder | 86% | 1131.81 | 18 / 21 | 44% | 4.97 | 224 / 504 |
pancreas | 22% | 165.45 | 73 / 328 | 81% | 14.24 | 144 / 178 |
adipose | 100% | 5180.22 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 98% | 2875.79 | 1307 / 1335 | 0% | 0 | 0 / 0 |
heart | 96% | 1529.52 | 827 / 861 | 0% | 0 | 0 / 0 |
skin | 59% | 527.67 | 1076 / 1809 | 29% | 3.59 | 137 / 472 |
liver | 27% | 166.04 | 60 / 226 | 55% | 6.56 | 222 / 406 |
spleen | 63% | 501.90 | 152 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 56% | 6.16 | 25 / 45 |
muscle | 42% | 309.22 | 336 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 14% | 1.01 | 4 / 29 |
peripheral blood | 2% | 15.04 | 22 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001525 | Biological process | angiogenesis |
GO_0031623 | Biological process | receptor internalization |
GO_1990410 | Biological process | adrenomedullin receptor signaling pathway |
GO_0007507 | Biological process | heart development |
GO_1990408 | Biological process | calcitonin gene-related peptide receptor signaling pathway |
GO_1990874 | Biological process | vascular associated smooth muscle cell proliferation |
GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
GO_0007187 | Biological process | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
GO_0015031 | Biological process | protein transport |
GO_1904707 | Biological process | positive regulation of vascular associated smooth muscle cell proliferation |
GO_0006816 | Biological process | calcium ion transport |
GO_0071329 | Biological process | cellular response to sucrose stimulus |
GO_0007166 | Biological process | cell surface receptor signaling pathway |
GO_0005886 | Cellular component | plasma membrane |
GO_0005764 | Cellular component | lysosome |
GO_1990406 | Cellular component | CGRP receptor complex |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005737 | Cellular component | cytoplasm |
GO_1903143 | Cellular component | adrenomedullin receptor complex |
GO_0005768 | Cellular component | endosome |
GO_0004930 | Molecular function | G protein-coupled receptor activity |
GO_1990409 | Molecular function | adrenomedullin binding |
GO_0001605 | Molecular function | adrenomedullin receptor activity |
GO_0001635 | Molecular function | calcitonin gene-related peptide receptor activity |
GO_0004948 | Molecular function | calcitonin receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | CALCRL |
Protein name | Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor) |
Synonyms | CGRPR |
Description | FUNCTION: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2 . The activity of this receptor is mediated by G proteins which activate adenylyl cyclase . . FUNCTION: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. . FUNCTION: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. . |
Accessions | ENST00000447403.5 ENST00000410068.5 E7EN01 Q16602 ENST00000410102.5 ENST00000409998.5 B8ZZJ4 ENST00000392370.8 |