IFT74 | OmnibusX

Name	Number of supported studies	Average coverage
ciliated cell	17 studies	32% ± 10%	Explore
epithelial cell	7 studies	28% ± 11%	Explore
astrocyte	6 studies	31% ± 13%	Explore
endothelial cell	4 studies	24% ± 6%	Explore
oligodendrocyte	4 studies	22% ± 8%	Explore
GABAergic neuron	3 studies	36% ± 5%	Explore
glutamatergic neuron	3 studies	42% ± 4%	Explore
oligodendrocyte precursor cell	3 studies	23% ± 5%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	31% ± 4%	Explore
liver	3 studies	18% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	981.15	245 / 245	100%	9.19	502 / 502
thymus	100%	1431.51	653 / 653	99%	11.19	600 / 605
breast	100%	868.71	459 / 459	99%	10.76	1102 / 1118
adrenal gland	100%	1182.08	258 / 258	98%	7.93	226 / 230
uterus	100%	1099.58	170 / 170	98%	6.81	448 / 459
pancreas	100%	449.80	327 / 328	98%	5.46	174 / 178
ovary	100%	1066.63	180 / 180	96%	6.35	414 / 430
bladder	100%	842.90	21 / 21	96%	6.46	482 / 504
kidney	100%	983.75	89 / 89	95%	7.07	856 / 901
brain	99%	437.05	2612 / 2642	96%	5.20	676 / 705
intestine	100%	890.19	966 / 966	94%	7.58	493 / 527
lung	99%	605.66	570 / 578	93%	5.31	1072 / 1155
stomach	100%	531.30	358 / 359	90%	6.76	257 / 286
esophagus	100%	716.39	1443 / 1445	87%	4.71	160 / 183
liver	100%	426.13	226 / 226	80%	3.46	324 / 406
skin	100%	764.52	1807 / 1809	77%	4.35	365 / 472
spleen	100%	726.32	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	3.72	1 / 1
adipose	100%	717.15	1203 / 1204	0%	0	0 / 0
blood vessel	100%	672.18	1333 / 1335	0%	0	0 / 0
muscle	99%	531.85	796 / 803	0%	0	0 / 0
heart	95%	485.40	817 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	89%	5.54	40 / 45
lymph node	0%	0	0 / 0	72%	3.25	21 / 29
eye	0%	0	0 / 0	51%	2.47	41 / 80
peripheral blood	25%	194.34	230 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_1905515	Biological process	non-motile cilium assembly
GO_0060271	Biological process	cilium assembly
GO_0033630	Biological process	positive regulation of cell adhesion mediated by integrin
GO_0007219	Biological process	Notch signaling pathway
GO_0007507	Biological process	heart development
GO_0007368	Biological process	determination of left/right symmetry
GO_0010839	Biological process	negative regulation of keratinocyte proliferation
GO_0035735	Biological process	intraciliary transport involved in cilium assembly
GO_0003334	Biological process	keratinocyte development
GO_0035720	Biological process	intraciliary anterograde transport
GO_0043616	Biological process	keratinocyte proliferation
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0001669	Cellular component	acrosomal vesicle
GO_0005813	Cellular component	centrosome
GO_0031514	Cellular component	motile cilium
GO_0030992	Cellular component	intraciliary transport particle B
GO_0097542	Cellular component	ciliary tip
GO_0005929	Cellular component	cilium
GO_0005634	Cellular component	nucleus
GO_0048487	Molecular function	beta-tubulin binding
GO_0003682	Molecular function	chromatin binding
GO_0005515	Molecular function	protein binding

Gene name	IFT74
Protein name	Intraflagellar transport 74 Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2) IFT74 protein
Synonyms	CCDC2 CMG1
Description	FUNCTION: Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium . Binds beta-tubulin via its basic region . Required for ciliogenesis . Essential for flagellogenesis during spermatogenesis . .
Accessions	ENST00000429045.6 [Q96LB3-2] Q96LB3 E5RH29 E5RGX6 ENST00000518614.5 E5RIF0 ENST00000648373.1 ENST00000433700.5 [Q96LB3-1] ENST00000517444.5 A0PJM7 ENST00000517866.1 Q8IUV3 A0A3B3IT46 E5RJK3 ENST00000380062.10 [Q96LB3-1] ENST00000519968.5 ENST00000443698.5 [Q96LB3-1]

IFT74 report