Insufficient scRNA-seq data for expression of FOXL1 at single-cell level.
Insufficient scRNA-seq data for expression of FOXL1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| stomach | 65% | 173.84 | 233 / 359 | 90% | 3.72 | 258 / 286 |
| intestine | 56% | 250.57 | 543 / 966 | 94% | 5.16 | 493 / 527 |
| lung | 83% | 231.61 | 478 / 578 | 62% | 2.42 | 712 / 1155 |
| bladder | 71% | 640.52 | 15 / 21 | 67% | 4.54 | 339 / 504 |
| kidney | 44% | 129.03 | 39 / 89 | 58% | 2.30 | 523 / 901 |
| blood vessel | 100% | 2127.66 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.98 | 1 / 1 |
| esophagus | 14% | 28.19 | 201 / 1445 | 85% | 4.34 | 155 / 183 |
| pancreas | 1% | 1.10 | 3 / 328 | 96% | 21.27 | 171 / 178 |
| uterus | 38% | 82.50 | 65 / 170 | 59% | 4.63 | 269 / 459 |
| breast | 50% | 105.40 | 230 / 459 | 41% | 1.20 | 458 / 1118 |
| prostate | 58% | 166.89 | 141 / 245 | 22% | 0.41 | 108 / 502 |
| heart | 70% | 181.18 | 602 / 861 | 0% | 0 | 0 / 0 |
| thymus | 40% | 74.15 | 258 / 653 | 22% | 0.35 | 131 / 605 |
| adipose | 58% | 179.53 | 702 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 57% | 202.27 | 460 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 53% | 1.57 | 24 / 45 |
| skin | 39% | 569.34 | 702 / 1809 | 14% | 0.58 | 66 / 472 |
| adrenal gland | 12% | 19.95 | 30 / 258 | 26% | 1.36 | 59 / 230 |
| brain | 7% | 11.94 | 192 / 2642 | 22% | 0.50 | 157 / 705 |
| ovary | 23% | 62.54 | 41 / 180 | 5% | 0.11 | 20 / 430 |
| lymph node | 0% | 0 | 0 / 0 | 21% | 1.81 | 6 / 29 |
| liver | 3% | 4.08 | 6 / 226 | 17% | 0.66 | 70 / 406 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.01 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_0061146 | Biological process | Peyer's patch morphogenesis |
| GO_0030166 | Biological process | proteoglycan biosynthetic process |
| GO_0007495 | Biological process | visceral mesoderm-endoderm interaction involved in midgut development |
| GO_0030111 | Biological process | regulation of Wnt signaling pathway |
| GO_0030154 | Biological process | cell differentiation |
| GO_0007507 | Biological process | heart development |
| GO_0009653 | Biological process | anatomical structure morphogenesis |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0008301 | Molecular function | DNA binding, bending |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0043565 | Molecular function | sequence-specific DNA binding |
| Gene name | FOXL1 |
| Protein name | Forkhead box L1 Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead-related transcription factor 7) (FREAC-7) |
| Synonyms | FKHL11 FREAC7 |
| Description | FUNCTION: Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 and GLI3 transcription factors (By similarity). . |
| Accessions | ENST00000320241.5 Q498Y4 M0R279 Q12952 ENST00000593625.1 |