MB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015671Biological processoxygen transport
GO_0043353Biological processenucleate erythrocyte differentiation
GO_0050873Biological processbrown fat cell differentiation
GO_0019430Biological processremoval of superoxide radicals
GO_0001666Biological processresponse to hypoxia
GO_0007507Biological processheart development
GO_0070062Cellular componentextracellular exosome
GO_0016528Cellular componentsarcoplasm
GO_0005829Cellular componentcytosol
GO_0005344Molecular functionoxygen carrier activity
GO_0004601Molecular functionperoxidase activity
GO_0019825Molecular functionoxygen binding
GO_0098809Molecular functionnitrite reductase activity
GO_0020037Molecular functionheme binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameMB
Protein nameMyoglobin (Nitrite reductase MB) (EC 1.7.-.-) (Pseudoperoxidase MB) (EC 1.11.1.-)
Myoglobin
SynonymsGLNG
hCG_41530
DescriptionFUNCTION: Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand . Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide . Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity . .

FUNCTION: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. .

FUNCTION: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. .

FUNCTION: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. .

FUNCTION: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. .

FUNCTION: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. .

FUNCTION: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. .

FUNCTION: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. .

FUNCTION: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. .

FUNCTION: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. .

AccessionsF2Z337
F2Z2F1
ENST00000442617.1
ENST00000397328.5
ENST00000443033.5
U6FM64
ENST00000397326.7
ENST00000406324.5
P02144
U6FJG6
ENST00000401702.5
A0A1K0FU49
ENST00000419229.1
U6FIV2
Q8WVH6
B0QYF8
ENST00000359787.5
U6FIU7
B0QYF7
ENST00000447607.5
ENST00000451685.5