GJA5 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GJA5 at tissue level.

III. Associated gene sets

GO_0098910Biological processregulation of atrial cardiac muscle cell action potential
GO_0086053Biological processAV node cell to bundle of His cell communication by electrical coupling
GO_0048844Biological processartery morphogenesis
GO_0060307Biological processregulation of ventricular cardiac muscle cell membrane repolarization
GO_0001525Biological processangiogenesis
GO_0003161Biological processcardiac conduction system development
GO_0003174Biological processmitral valve development
GO_0006813Biological processpotassium ion transport
GO_0003151Biological processoutflow tract morphogenesis
GO_1990029Biological processvasomotion
GO_0010643Biological processcell communication by chemical coupling
GO_0007507Biological processheart development
GO_0055085Biological processtransmembrane transport
GO_0086064Biological processcell communication by electrical coupling involved in cardiac conduction
GO_0098904Biological processregulation of AV node cell action potential
GO_0086044Biological processatrial cardiac muscle cell to AV node cell communication by electrical coupling
GO_0098905Biological processregulation of bundle of His cell action potential
GO_0045907Biological processpositive regulation of vasoconstriction
GO_0060373Biological processregulation of ventricular cardiac muscle cell membrane depolarization
GO_0003281Biological processventricular septum development
GO_0010652Biological processpositive regulation of cell communication by chemical coupling
GO_0086021Biological processSA node cell to atrial cardiac muscle cell communication by electrical coupling
GO_0007267Biological processcell-cell signaling
GO_0003193Biological processpulmonary valve formation
GO_0003283Biological processatrial septum development
GO_0045776Biological processnegative regulation of blood pressure
GO_0060371Biological processregulation of atrial cardiac muscle cell membrane depolarization
GO_0003158Biological processendothelium development
GO_0010649Biological processregulation of cell communication by electrical coupling
GO_0003105Biological processnegative regulation of glomerular filtration
GO_0086054Biological processbundle of His cell to Purkinje myocyte communication by electrical coupling
GO_0016264Biological processgap junction assembly
GO_0042311Biological processvasodilation
GO_0098906Biological processregulation of Purkinje myocyte action potential
GO_0055117Biological processregulation of cardiac muscle contraction
GO_0086055Biological processPurkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling
GO_0005886Cellular componentplasma membrane
GO_0005922Cellular componentconnexin complex
GO_0005921Cellular componentgap junction
GO_0042995Cellular componentcell projection
GO_0014704Cellular componentintercalated disc
GO_0071253Molecular functionconnexin binding
GO_0086076Molecular functiongap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling
GO_0086079Molecular functiongap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling
GO_0086077Molecular functiongap junction channel activity involved in AV node cell-bundle of His cell electrical coupling
GO_0086078Molecular functiongap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling
GO_0086075Molecular functiongap junction channel activity involved in cardiac conduction electrical coupling
GO_0097718Molecular functiondisordered domain specific binding
GO_0005515Molecular functionprotein binding
GO_0055077Molecular functiongap junction hemi-channel activity
GO_0086020Molecular functiongap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling

IV. Literature review

[source]
Gene nameGJA5
Protein nameGap junction protein
Gap junction alpha-5 protein (Connexin-40) (Cx40)
SynonymsCXNI
hCG_1770483
DescriptionFUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

AccessionsX5D2H9
A0A0B4J1Y3
ENST00000621517.1
ENST00000579774.3
P36382
ENST00000430508.1