COL6A1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	48 studies	65% ± 20%	Explore
pericyte	37 studies	45% ± 18%	Explore
smooth muscle cell	32 studies	45% ± 15%	Explore
connective tissue cell	18 studies	63% ± 21%	Explore
myofibroblast cell	15 studies	59% ± 17%	Explore
endothelial cell	11 studies	27% ± 9%	Explore
mesothelial cell	10 studies	44% ± 17%	Explore
adipocyte	9 studies	38% ± 28%	Explore
renal alpha-intercalated cell	5 studies	37% ± 13%	Explore
adventitial cell	5 studies	70% ± 16%	Explore
kidney loop of Henle epithelial cell	4 studies	19% ± 3%	Explore
myoepithelial cell	4 studies	36% ± 21%	Explore
oligodendrocyte precursor cell	4 studies	23% ± 6%	Explore
progenitor cell	3 studies	38% ± 7%	Explore
glial cell	3 studies	29% ± 14%	Explore
epithelial cell	3 studies	31% ± 20%	Explore
neuron	3 studies	29% ± 13%	Explore
muscle cell	3 studies	46% ± 10%	Explore
astrocyte	3 studies	25% ± 0%	Explore
glutamatergic neuron	3 studies	42% ± 8%	Explore
Schwann cell	3 studies	24% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
intestine	5 studies	44% ± 15%	Explore
lung	5 studies	36% ± 17%	Explore
heart	5 studies	21% ± 4%	Explore
adipose	5 studies	38% ± 31%	Explore
uterus	4 studies	32% ± 5%	Explore
esophagus	3 studies	28% ± 11%	Explore
skin	3 studies	28% ± 9%	Explore
brain	3 studies	26% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	99%	60419.95	456 / 459	97%	570.19	1080 / 1118
skin	89%	96276.32	1617 / 1809	95%	443.57	449 / 472
ovary	100%	138396.44	180 / 180	84%	296.59	363 / 430
lung	97%	45300.57	563 / 578	87%	237.47	1000 / 1155
bladder	100%	140373.90	21 / 21	78%	253.21	392 / 504
intestine	94%	143149.05	911 / 966	83%	224.88	436 / 527
esophagus	88%	118410.12	1266 / 1445	89%	334.88	163 / 183
prostate	99%	80712.02	243 / 245	75%	114.39	379 / 502
uterus	99%	167372.38	169 / 170	75%	372.69	342 / 459
thymus	92%	29357.11	600 / 653	63%	155.88	382 / 605
stomach	65%	55954.39	234 / 359	90%	265.24	256 / 286
kidney	66%	16600.44	59 / 89	85%	181.27	762 / 901
adrenal gland	53%	11593.38	137 / 258	65%	105.05	150 / 230
brain	19%	6487.99	494 / 2642	83%	194.49	584 / 705
pancreas	7%	1716.44	24 / 328	93%	385.85	165 / 178
adipose	100%	87858.27	1204 / 1204	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	70.32	1 / 1
blood vessel	100%	97857.68	1333 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	213.43	28 / 29
eye	0%	0	0 / 0	95%	149.26	76 / 80
heart	91%	33359.91	786 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	76%	261.54	34 / 45
spleen	76%	21341.40	182 / 241	0%	0	0 / 0
liver	11%	2927.17	25 / 226	45%	72.72	182 / 406
muscle	14%	3445.91	115 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006954	Biological process	inflammatory response
GO_0006096	Biological process	glycolytic process
GO_0048009	Biological process	insulin-like growth factor receptor signaling pathway
GO_0048741	Biological process	skeletal muscle fiber development
GO_0070341	Biological process	fat cell proliferation
GO_0009411	Biological process	response to UV
GO_0048872	Biological process	homeostasis of number of cells
GO_0051262	Biological process	protein tetramerization
GO_0048771	Biological process	tissue remodeling
GO_0051402	Biological process	neuron apoptotic process
GO_0006099	Biological process	tricarboxylic acid cycle
GO_0002023	Biological process	reduction of food intake in response to dietary excess
GO_0098528	Biological process	skeletal muscle fiber differentiation
GO_0043491	Biological process	phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0006914	Biological process	autophagy
GO_0000902	Biological process	cell morphogenesis
GO_0009612	Biological process	response to mechanical stimulus
GO_0009410	Biological process	response to xenobiotic stimulus
GO_1990542	Biological process	mitochondrial transmembrane transport
GO_0085029	Biological process	extracellular matrix assembly
GO_0001649	Biological process	osteoblast differentiation
GO_0035987	Biological process	endodermal cell differentiation
GO_0010657	Biological process	muscle cell apoptotic process
GO_0043403	Biological process	skeletal muscle tissue regeneration
GO_0007155	Biological process	cell adhesion
GO_0072593	Biological process	reactive oxygen species metabolic process
GO_0071965	Biological process	multicellular organismal locomotion
GO_0071711	Biological process	basement membrane organization
GO_0050954	Biological process	sensory perception of mechanical stimulus
GO_0048265	Biological process	response to pain
GO_0060425	Biological process	lung morphogenesis
GO_0000302	Biological process	response to reactive oxygen species
GO_0010467	Biological process	gene expression
GO_0060348	Biological process	bone development
GO_0051216	Biological process	cartilage development
GO_0032963	Biological process	collagen metabolic process
GO_1904583	Biological process	response to polyamine macromolecule
GO_1901652	Biological process	response to peptide
GO_0030262	Biological process	apoptotic nuclear changes
GO_1904975	Biological process	response to bleomycin
GO_0007005	Biological process	mitochondrion organization
GO_0008286	Biological process	insulin receptor signaling pathway
GO_0060065	Biological process	uterus development
GO_0071230	Biological process	cellular response to amino acid stimulus
GO_0060612	Biological process	adipose tissue development
GO_0030199	Biological process	collagen fibril organization
GO_0007338	Biological process	single fertilization
GO_0009636	Biological process	response to toxic substance
GO_0009611	Biological process	response to wounding
GO_0060487	Biological process	lung epithelial cell differentiation
GO_0048286	Biological process	lung alveolus development
GO_0036293	Biological process	response to decreased oxygen levels
GO_0006103	Biological process	2-oxoglutarate metabolic process
GO_0036022	Biological process	limb joint morphogenesis
GO_0007507	Biological process	heart development
GO_0070836	Biological process	caveola assembly
GO_0007623	Biological process	circadian rhythm
GO_0014850	Biological process	response to muscle activity
GO_0022011	Biological process	myelination in peripheral nervous system
GO_0060070	Biological process	canonical Wnt signaling pathway
GO_0003012	Biological process	muscle system process
GO_0003016	Biological process	respiratory system process
GO_0030282	Biological process	bone mineralization
GO_0051882	Biological process	mitochondrial depolarization
GO_0001942	Biological process	hair follicle development
GO_1904026	Biological process	regulation of collagen fibril organization
GO_0019226	Biological process	transmission of nerve impulse
GO_0008361	Biological process	regulation of cell size
GO_0048630	Biological process	skeletal muscle tissue growth
GO_0006112	Biological process	energy reserve metabolic process
GO_0032496	Biological process	response to lipopolysaccharide
GO_0005788	Cellular component	endoplasmic reticulum lumen
GO_0005576	Cellular component	extracellular region
GO_0070062	Cellular component	extracellular exosome
GO_0016020	Cellular component	membrane
GO_0005739	Cellular component	mitochondrion
GO_0030016	Cellular component	myofibril
GO_0032991	Cellular component	protein-containing complex
GO_0097708	Cellular component	intracellular vesicle
GO_0016529	Cellular component	sarcoplasmic reticulum
GO_0005765	Cellular component	lysosomal membrane
GO_0005589	Cellular component	collagen type VI trimer
GO_0042383	Cellular component	sarcolemma
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0005604	Cellular component	basement membrane
GO_0030020	Molecular function	extracellular matrix structural constituent conferring tensile strength
GO_0005518	Molecular function	collagen binding
GO_0048407	Molecular function	platelet-derived growth factor binding

Gene name	COL6A1
Protein name	Collagen alpha-1(VI) chain COL6A1 protein Collagen, type VI, alpha 1, isoform CRA_b (Epididymis secretory sperm binding protein) Collagen type VI alpha 1 chain
Synonyms	hCG_401279
Description	FUNCTION: Collagen VI acts as a cell-binding protein.
Accessions	Q05BT9 ENST00000612273.2 A0A087X0S5 ENST00000361866.8 ENST00000682634.1 P12109 A0A804HJ28 A0A384P5H7

COL6A1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review