Biological process

PI3K-PKB/Akt pathway, PI3K/Akt signal transduction, PI3K/PKB signal transduction, phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction

An intracellular signaling cassette that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway.

AKT signal transduction, AKT signaling, AKT signaling cascade, AKT signalling cascade, PKB signal transduction, PKB signaling, PKB signaling cascade, PKB signalling cascade, protein kinase B signal transduction, protein kinase B signaling, protein kinase B signaling cascade, protein kinase B signalling cascade