MYO16 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0048812Biological processneuron projection morphogenesis
GO_0021549Biological processcerebellum development
GO_2000134Biological processnegative regulation of G1/S transition of mitotic cell cycle
GO_0043491Biological processphosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0005654Cellular componentnucleoplasm
GO_0005886Cellular componentplasma membrane
GO_0016459Cellular componentmyosin complex
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005737Cellular componentcytoplasm
GO_0003774Molecular functioncytoskeletal motor activity
GO_0051015Molecular functionactin filament binding
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding
GO_0019903Molecular functionprotein phosphatase binding

IV. Literature review

[source]
Gene nameMYO16
Protein nameUnconventional myosin-XVI (Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3) (Unconventional myosin-16)
Myosin XVI
SynonymsKIAA0865
MYO16B
NYAP3
DescriptionFUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development. Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis (By similarity). .

AccessionsF8W883
ENST00000457511.7
ENST00000356711.7 [Q9Y6X6-1]
Q9Y6X6
ENST00000251041.10 [Q9Y6X6-3]