PRR5L | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte	15 studies	45% ± 17%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	21% ± 6%	Explore
natural killer cell	5 studies	20% ± 4%	Explore
endothelial cell of lymphatic vessel	5 studies	24% ± 4%	Explore
oligodendrocyte precursor cell	5 studies	25% ± 7%	Explore
endothelial cell	4 studies	26% ± 6%	Explore
astrocyte	3 studies	31% ± 7%	Explore

Name	Number of supported studies	Average coverage
brain	7 studies	29% ± 13%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	97%	702.26	2571 / 2642	98%	11.77	692 / 705
ovary	99%	1748.09	179 / 180	95%	7.67	408 / 430
lung	100%	1283.13	577 / 578	93%	9.23	1074 / 1155
breast	97%	394.07	447 / 459	91%	5.93	1022 / 1118
uterus	100%	495.19	170 / 170	83%	7.77	381 / 459
kidney	99%	515.78	88 / 89	76%	5.71	682 / 901
intestine	79%	1718.76	761 / 966	95%	18.98	502 / 527
thymus	99%	470.42	648 / 653	59%	3.60	359 / 605
bladder	86%	436.62	18 / 21	69%	8.75	346 / 504
stomach	54%	109.91	194 / 359	93%	13.89	267 / 286
skin	81%	334.97	1470 / 1809	62%	3.20	293 / 472
esophagus	52%	108.20	749 / 1445	80%	6.97	147 / 183
prostate	97%	367.03	237 / 245	32%	0.96	163 / 502
pancreas	28%	62.77	93 / 328	93%	10.47	165 / 178
adrenal gland	79%	210.74	203 / 258	22%	0.85	50 / 230
spleen	100%	4934.80	241 / 241	0%	0	0 / 0
adipose	97%	446.79	1171 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	89%	10.59	40 / 45
peripheral blood	74%	682.73	687 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	72%	5.27	21 / 29
liver	35%	63.53	79 / 226	30%	2.41	120 / 406
blood vessel	60%	185.08	807 / 1335	0%	0	0 / 0
heart	47%	113.66	405 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	16%	0.59	13 / 80
muscle	6%	9.17	45 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0010762	Biological process	regulation of fibroblast migration
GO_0001933	Biological process	negative regulation of protein phosphorylation
GO_0051897	Biological process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0034599	Biological process	cellular response to oxidative stress
GO_0001934	Biological process	positive regulation of protein phosphorylation
GO_0090316	Biological process	positive regulation of intracellular protein transport
GO_0061014	Biological process	positive regulation of mRNA catabolic process
GO_0038203	Biological process	TORC2 signaling
GO_0009968	Biological process	negative regulation of signal transduction
GO_0043491	Biological process	phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0031932	Cellular component	TORC2 complex
GO_0031625	Molecular function	ubiquitin protein ligase binding
GO_0005515	Molecular function	protein binding

Gene name	PRR5L
Protein name	Proline-rich protein 5-like (Protein observed with Rictor-2) (Protor-2) Proline rich 5 like
Synonyms	PROTOR2
Description	FUNCTION: Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton . Regulates the activity of the mTORC2 complex in a substrate-specific manner preventing for instance the specific phosphorylation of PKCs and thereby controlling cell migration . Plays a role in the stimulation of ZFP36-mediated mRNA decay of several ZFP36-associated mRNAs, such as TNF-alpha and GM-CSF, in response to stress . Required for ZFP36 localization to cytoplasmic stress granule (SG) and P-body (PB) in response to stress . .
Accessions	ENST00000527487.1 [Q6MZQ0-4] ENST00000527172.5 E9PS02 ENST00000526728.5 ENST00000524380.5 Q6MZQ0 ENST00000530252.1 E9PP62 ENST00000530050.5 ENST00000526679.1 E9PJV4 E9PL62 ENST00000378867.7 [Q6MZQ0-1] E9PIU0 ENST00000526682.5 ENST00000532121.5 E9PP25 ENST00000530639.6 [Q6MZQ0-1] E9PLJ6

PRR5L report