C1QTNF12 | OmnibusX

Name	Number of supported studies	Average coverage
enterocyte	5 studies	24% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of C1QTNF12 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	99%	240.55	960 / 966	91%	6.64	480 / 527
esophagus	97%	64.70	1404 / 1445	91%	10.99	166 / 183
thymus	99%	60.44	644 / 653	84%	9.83	511 / 605
ovary	95%	42.00	171 / 180	88%	5.64	377 / 430
kidney	100%	229.25	89 / 89	81%	4.55	730 / 901
bladder	100%	53.38	21 / 21	77%	5.18	390 / 504
stomach	91%	45.67	325 / 359	85%	6.74	242 / 286
uterus	98%	46.29	167 / 170	74%	5.28	340 / 459
lung	97%	70.53	559 / 578	73%	6.84	843 / 1155
brain	87%	40.42	2292 / 2642	64%	1.50	454 / 705
breast	99%	81.75	456 / 459	40%	1.31	446 / 1118
pancreas	48%	13.52	157 / 328	89%	6.59	159 / 178
skin	98%	217.22	1778 / 1809	33%	1.33	157 / 472
prostate	96%	51.90	234 / 245	35%	0.57	174 / 502
liver	92%	46.75	209 / 226	32%	1.32	128 / 406
adrenal gland	69%	20.57	177 / 258	33%	0.62	76 / 230
ureter	0%	0	0 / 0	100%	4.25	1 / 1
adipose	98%	81.28	1179 / 1204	0%	0	0 / 0
spleen	95%	44.46	230 / 241	0%	0	0 / 0
blood vessel	94%	50.14	1253 / 1335	0%	0	0 / 0
peripheral blood	77%	32.39	716 / 929	0%	0	0 / 0
heart	74%	30.36	639 / 861	0%	0	0 / 0
muscle	64%	21.34	513 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	62%	7.18	28 / 45
eye	0%	0	0 / 0	57%	1.97	46 / 80
lymph node	0%	0	0 / 0	48%	0.68	14 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0051897	Biological process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0050728	Biological process	negative regulation of inflammatory response
GO_0046323	Biological process	glucose import
GO_0046326	Biological process	positive regulation of glucose import
GO_0006094	Biological process	gluconeogenesis
GO_0045721	Biological process	negative regulation of gluconeogenesis
GO_0051649	Biological process	establishment of localization in cell
GO_0046324	Biological process	regulation of glucose import
GO_0043491	Biological process	phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0046628	Biological process	positive regulation of insulin receptor signaling pathway
GO_0035774	Biological process	positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0005179	Molecular function	hormone activity

Gene name	C1QTNF12
Protein name	Adipolin (Adipose-derived insulin-sensitizing factor) (C1q and TNF related protein 12) (Complement C1q tumor necrosis factor-related protein 12) [Cleaved into: Adipolin fC1QTNF12 (Adipolin fCTRP12) (Adipolin full-length form); Adipolin gC1QTNF12 (Adipolin cleaved form) (Adipolin gCTRP12)]
Synonyms	FAM132A CTRP12 C1QDC2
Description	FUNCTION: Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue. .
Accessions	ENST00000330388.2 Q5T7M4

C1QTNF12 report