SERPINA12 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SERPINA12 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SERPINA12 at tissue level.

III. Associated gene sets

GO_0090181Biological processregulation of cholesterol metabolic process
GO_0051897Biological processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0051055Biological processnegative regulation of lipid biosynthetic process
GO_0090207Biological processregulation of triglyceride metabolic process
GO_0008610Biological processlipid biosynthetic process
GO_0006094Biological processgluconeogenesis
GO_0045721Biological processnegative regulation of gluconeogenesis
GO_0010951Biological processnegative regulation of endopeptidase activity
GO_0043491Biological processphosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0046628Biological processpositive regulation of insulin receptor signaling pathway
GO_0005615Cellular componentextracellular space
GO_0005886Cellular componentplasma membrane
GO_0004867Molecular functionserine-type endopeptidase inhibitor activity
GO_0140678Molecular functionmolecular function inhibitor activity

IV. Literature review

[source]
Gene nameSERPINA12
Protein nameSerpin A12 (OL-64) (Visceral adipose tissue-derived serine protease inhibitor) (Vaspin) (Visceral adipose-specific serpin)
Synonyms
DescriptionFUNCTION: Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues. .

AccessionsENST00000677451.1
Q8IW75
ENST00000341228.2
ENST00000556881.5