Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 4156.43 | 578 / 578 | 95% | 5.71 | 1093 / 1155 |
breast | 83% | 732.01 | 380 / 459 | 96% | 4.96 | 1076 / 1118 |
intestine | 82% | 1041.60 | 795 / 966 | 75% | 2.74 | 397 / 527 |
bladder | 86% | 825.67 | 18 / 21 | 69% | 2.65 | 347 / 504 |
adrenal gland | 96% | 1103.24 | 248 / 258 | 57% | 1.37 | 130 / 230 |
stomach | 64% | 419.37 | 230 / 359 | 82% | 3.59 | 235 / 286 |
esophagus | 57% | 359.92 | 825 / 1445 | 82% | 3.31 | 150 / 183 |
thymus | 56% | 423.17 | 365 / 653 | 82% | 4.37 | 498 / 605 |
prostate | 61% | 417.64 | 149 / 245 | 76% | 1.84 | 382 / 502 |
kidney | 40% | 359.84 | 36 / 89 | 91% | 6.67 | 819 / 901 |
skin | 35% | 184.69 | 638 / 1809 | 88% | 4.99 | 415 / 472 |
uterus | 42% | 220.58 | 71 / 170 | 80% | 2.61 | 369 / 459 |
brain | 17% | 101.35 | 459 / 2642 | 96% | 6.25 | 680 / 705 |
pancreas | 21% | 132.70 | 68 / 328 | 90% | 5.89 | 161 / 178 |
peripheral blood | 100% | 11218.47 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 7017.41 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 98% | 1486.47 | 1176 / 1204 | 0% | 0 | 0 / 0 |
liver | 40% | 244.93 | 90 / 226 | 56% | 1.53 | 229 / 406 |
ovary | 19% | 117.62 | 35 / 180 | 77% | 2.53 | 330 / 430 |
tonsil | 0% | 0 | 0 / 0 | 96% | 4.90 | 43 / 45 |
lymph node | 0% | 0 | 0 / 0 | 93% | 11.72 | 27 / 29 |
blood vessel | 63% | 657.33 | 839 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 46% | 1.43 | 37 / 80 |
heart | 37% | 235.29 | 322 / 861 | 0% | 0 | 0 / 0 |
muscle | 2% | 10.94 | 19 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0043406 | Biological process | positive regulation of MAP kinase activity |
GO_0006955 | Biological process | immune response |
GO_0043491 | Biological process | phosphatidylinositol 3-kinase/protein kinase B signal transduction |
GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0046488 | Biological process | phosphatidylinositol metabolic process |
GO_0005943 | Cellular component | phosphatidylinositol 3-kinase complex, class IA |
GO_0005944 | Cellular component | phosphatidylinositol 3-kinase complex, class IB |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0005942 | Cellular component | phosphatidylinositol 3-kinase complex |
GO_0034451 | Cellular component | centriolar satellite |
GO_0016020 | Cellular component | membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0031683 | Molecular function | G-protein beta/gamma-subunit complex binding |
GO_0046935 | Molecular function | 1-phosphatidylinositol-3-kinase regulator activity |
Gene name | PIK3R5 |
Protein name | Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit) (Protein FOAP-2) (PtdIns-3-kinase p101) (p101-PI3K) Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide-3-kinase regulatory subunit 5 |
Synonyms | |
Description | FUNCTION: Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG (By similarity). . |
Accessions | ENST00000584803.1 J3KT66 ENST00000611902.4 [Q8WYR1-2] ENST00000581552.5 [Q8WYR1-1] L7RT34 Q8WYR1 ENST00000447110.6 [Q8WYR1-1] ENST00000616147.4 [Q8WYR1-2] J3KRE9 ENST00000581895.1 J3KSW1 ENST00000269300.8 ENST00000623421.3 [Q8WYR1-2] ENST00000585260.5 X6R3K3 |