PIK3R5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0043406Biological processpositive regulation of MAP kinase activity
GO_0006955Biological processimmune response
GO_0043491Biological processphosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0051897Biological processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0046488Biological processphosphatidylinositol metabolic process
GO_0005943Cellular componentphosphatidylinositol 3-kinase complex, class IA
GO_0005944Cellular componentphosphatidylinositol 3-kinase complex, class IB
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005942Cellular componentphosphatidylinositol 3-kinase complex
GO_0034451Cellular componentcentriolar satellite
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0031683Molecular functionG-protein beta/gamma-subunit complex binding
GO_0046935Molecular function1-phosphatidylinositol-3-kinase regulator activity

IV. Literature review

[source]
Gene namePIK3R5
Protein namePhosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit) (Protein FOAP-2) (PtdIns-3-kinase p101) (p101-PI3K)
Phosphoinositide 3-kinase regulatory subunit 5
Phosphoinositide-3-kinase regulatory subunit 5
Synonyms
DescriptionFUNCTION: Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG (By similarity). .

AccessionsENST00000584803.1
J3KT66
ENST00000611902.4 [Q8WYR1-2]
ENST00000581552.5 [Q8WYR1-1]
L7RT34
Q8WYR1
ENST00000447110.6 [Q8WYR1-1]
ENST00000616147.4 [Q8WYR1-2]
J3KRE9
ENST00000581895.1
J3KSW1
ENST00000269300.8
ENST00000623421.3 [Q8WYR1-2]
ENST00000585260.5
X6R3K3