Name | phosphatidylinositol 3-kinase complex, class IA |
ID | GO_0005943 |
collection_id | Cellular component |
Alternative ID | GO:0035030 |
Exact synonym | 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex, 1-phosphatidylinositol-4-phosphate kinase, class IA complex, class IA PI3K complex, phosphoinositide 3-kinase complex, class IA |
Description | A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways. |
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