Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| B cell | 48 studies | 59% ± 22% | |
| memory B cell | 20 studies | 72% ± 13% | |
| naive B cell | 20 studies | 62% ± 12% | |
| adipocyte | 8 studies | 25% ± 5% | |
| immature B cell | 6 studies | 54% ± 13% | |
| type I pneumocyte | 5 studies | 26% ± 3% | |
| type II pneumocyte | 5 studies | 17% ± 1% | |
| plasma cell | 3 studies | 26% ± 9% | |
| precursor B cell | 3 studies | 32% ± 16% | |
| germinal center B cell | 3 studies | 26% ± 3% |
Insufficient scRNA-seq data for expression of BANK1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 958.92 | 652 / 653 | 95% | 12.31 | 577 / 605 |
| prostate | 98% | 402.31 | 239 / 245 | 93% | 23.79 | 465 / 502 |
| lung | 99% | 518.59 | 574 / 578 | 76% | 5.48 | 875 / 1155 |
| kidney | 96% | 253.25 | 85 / 89 | 66% | 3.50 | 592 / 901 |
| adrenal gland | 99% | 453.07 | 256 / 258 | 40% | 2.25 | 93 / 230 |
| bladder | 67% | 240.57 | 14 / 21 | 52% | 3.03 | 262 / 504 |
| breast | 86% | 342.04 | 396 / 459 | 24% | 1.83 | 267 / 1118 |
| spleen | 100% | 5808.82 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 100% | 505.10 | 1200 / 1204 | 0% | 0 | 0 / 0 |
| esophagus | 55% | 97.02 | 795 / 1445 | 44% | 2.68 | 81 / 183 |
| peripheral blood | 96% | 657.44 | 889 / 929 | 0% | 0 | 0 / 0 |
| stomach | 51% | 88.98 | 184 / 359 | 43% | 2.70 | 122 / 286 |
| pancreas | 10% | 9.76 | 33 / 328 | 80% | 6.46 | 142 / 178 |
| lymph node | 0% | 0 | 0 / 0 | 90% | 27.61 | 26 / 29 |
| intestine | 53% | 937.80 | 511 / 966 | 35% | 2.38 | 182 / 527 |
| skin | 44% | 61.03 | 794 / 1809 | 20% | 2.82 | 95 / 472 |
| brain | 53% | 92.80 | 1395 / 2642 | 8% | 0.34 | 55 / 705 |
| ovary | 7% | 9.49 | 13 / 180 | 49% | 2.28 | 210 / 430 |
| tonsil | 0% | 0 | 0 / 0 | 53% | 3.81 | 24 / 45 |
| blood vessel | 47% | 116.40 | 631 / 1335 | 0% | 0 | 0 / 0 |
| uterus | 8% | 11.68 | 14 / 170 | 28% | 1.31 | 130 / 459 |
| heart | 21% | 36.00 | 185 / 861 | 0% | 0 | 0 / 0 |
| liver | 6% | 5.96 | 13 / 226 | 7% | 0.61 | 28 / 406 |
| muscle | 2% | 2.22 | 15 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.09 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0050853 | Biological process | B cell receptor signaling pathway |
| GO_0050731 | Biological process | positive regulation of peptidyl-tyrosine phosphorylation |
| GO_0051898 | Biological process | negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0043410 | Biological process | positive regulation of MAPK cascade |
| GO_0042113 | Biological process | B cell activation |
| GO_0000165 | Biological process | MAPK cascade |
| GO_0045947 | Biological process | negative regulation of translational initiation |
| GO_0032715 | Biological process | negative regulation of interleukin-6 production |
| GO_0043491 | Biological process | phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0009617 | Biological process | response to bacterium |
| GO_0050869 | Biological process | negative regulation of B cell activation |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0002020 | Molecular function | protease binding |
| GO_0035591 | Molecular function | signaling adaptor activity |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0005515 | Molecular function | protein binding |
| GO_1990782 | Molecular function | protein tyrosine kinase binding |
| GO_0043274 | Molecular function | phospholipase binding |
| Gene name | BANK1 |
| Protein name | B-cell scaffold protein with ankyrin repeats |
| Synonyms | |
| Description | FUNCTION: Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2. . |
| Accessions | ENST00000508653.5 [Q8NDB2-4] ENST00000428908.5 [Q8NDB2-4] ENST00000504592.5 [Q8NDB2-2] ENST00000322953.9 [Q8NDB2-1] ENST00000444316.2 [Q8NDB2-3] Q8NDB2 |
