Insufficient scRNA-seq data for expression of BTN2A2 at single-cell level.
Insufficient scRNA-seq data for expression of BTN2A2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 100% | 867.17 | 1807 / 1809 | 100% | 29.37 | 471 / 472 |
| breast | 100% | 1069.41 | 458 / 459 | 99% | 9.28 | 1106 / 1118 |
| thymus | 100% | 1000.51 | 653 / 653 | 99% | 7.86 | 597 / 605 |
| kidney | 100% | 887.78 | 89 / 89 | 98% | 13.12 | 882 / 901 |
| lung | 100% | 1963.38 | 578 / 578 | 97% | 9.81 | 1126 / 1155 |
| uterus | 100% | 1301.50 | 170 / 170 | 96% | 8.86 | 441 / 459 |
| prostate | 100% | 1125.77 | 245 / 245 | 95% | 5.62 | 479 / 502 |
| bladder | 100% | 655.29 | 21 / 21 | 93% | 6.51 | 471 / 504 |
| intestine | 100% | 985.09 | 966 / 966 | 93% | 5.27 | 492 / 527 |
| ovary | 100% | 1244.14 | 180 / 180 | 92% | 5.23 | 396 / 430 |
| esophagus | 100% | 729.80 | 1441 / 1445 | 92% | 5.53 | 169 / 183 |
| pancreas | 95% | 377.70 | 310 / 328 | 96% | 7.50 | 170 / 178 |
| adrenal gland | 100% | 1672.21 | 258 / 258 | 90% | 6.37 | 206 / 230 |
| stomach | 95% | 520.65 | 342 / 359 | 93% | 5.26 | 267 / 286 |
| brain | 90% | 718.52 | 2369 / 2642 | 97% | 7.75 | 681 / 705 |
| liver | 86% | 302.37 | 195 / 226 | 89% | 5.56 | 360 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 26.14 | 29 / 29 |
| spleen | 100% | 2571.39 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 100% | 889.08 | 1200 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 845.01 | 1328 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 94% | 10.42 | 75 / 80 |
| heart | 92% | 387.31 | 793 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 91% | 1263.58 | 850 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 10.72 | 41 / 45 |
| muscle | 38% | 98.94 | 302 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_2000134 | Biological process | negative regulation of G1/S transition of mitotic cell cycle |
| GO_0070373 | Biological process | negative regulation of ERK1 and ERK2 cascade |
| GO_0070371 | Biological process | ERK1 and ERK2 cascade |
| GO_0046007 | Biological process | negative regulation of activated T cell proliferation |
| GO_0051898 | Biological process | negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0045591 | Biological process | positive regulation of regulatory T cell differentiation |
| GO_0050860 | Biological process | negative regulation of T cell receptor signaling pathway |
| GO_0001817 | Biological process | regulation of cytokine production |
| GO_0050852 | Biological process | T cell receptor signaling pathway |
| GO_0000082 | Biological process | G1/S transition of mitotic cell cycle |
| GO_0043491 | Biological process | phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0001818 | Biological process | negative regulation of cytokine production |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005102 | Molecular function | signaling receptor binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | BTN2A2 |
| Protein name | Butyrophilin subfamily 2 member A2 |
| Synonyms | BT2.2 BTF2 |
| Description | FUNCTION: Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. . |
| Accessions | C9IZY2 ENST00000483410.1 ENST00000416795.6 [Q8WVV5-1] ENST00000432533.6 [Q8WVV5-3] ENST00000482536.5 [Q8WVV5-5] F8WC65 H7C4E8 ENST00000490025.5 Q8WVV5 ENST00000495632.1 C9J8J5 C9JWH2 ENST00000482842.1 C9IY66 ENST00000356709.9 [Q8WVV5-1] C9J8R3 ENST00000352867.6 [Q8WVV5-4] ENST00000471116.5 ENST00000472507.5 ENST00000493275.5 ENST00000494184.1 C9JAJ6 ENST00000469230.5 [Q8WVV5-2] |