BTN2A2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of BTN2A2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of BTN2A2 at tissue level.

III. Associated gene sets

GO_2000134Biological processnegative regulation of G1/S transition of mitotic cell cycle
GO_0070373Biological processnegative regulation of ERK1 and ERK2 cascade
GO_0070371Biological processERK1 and ERK2 cascade
GO_0046007Biological processnegative regulation of activated T cell proliferation
GO_0051898Biological processnegative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0045591Biological processpositive regulation of regulatory T cell differentiation
GO_0050860Biological processnegative regulation of T cell receptor signaling pathway
GO_0001817Biological processregulation of cytokine production
GO_0050852Biological processT cell receptor signaling pathway
GO_0000082Biological processG1/S transition of mitotic cell cycle
GO_0043491Biological processphosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0001818Biological processnegative regulation of cytokine production
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0005102Molecular functionsignaling receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameBTN2A2
Protein nameButyrophilin subfamily 2 member A2
SynonymsBT2.2
BTF2
DescriptionFUNCTION: Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. .

AccessionsC9IZY2
ENST00000483410.1
ENST00000416795.6 [Q8WVV5-1]
ENST00000432533.6 [Q8WVV5-3]
ENST00000482536.5 [Q8WVV5-5]
F8WC65
H7C4E8
ENST00000490025.5
Q8WVV5
ENST00000495632.1
C9J8J5
C9JWH2
ENST00000482842.1
C9IY66
ENST00000356709.9 [Q8WVV5-1]
C9J8R3
ENST00000352867.6 [Q8WVV5-4]
ENST00000471116.5
ENST00000472507.5
ENST00000493275.5
ENST00000494184.1
C9JAJ6
ENST00000469230.5 [Q8WVV5-2]