Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 15 studies | 37% ± 19% | |
| fibroblast | 7 studies | 32% ± 13% | |
| endothelial cell | 5 studies | 20% ± 6% | |
| adipocyte | 5 studies | 27% ± 6% | |
| oligodendrocyte precursor cell | 4 studies | 27% ± 9% | |
| GABAergic neuron | 3 studies | 26% ± 8% | |
| endothelial cell of artery | 3 studies | 25% ± 4% | |
| ependymal cell | 3 studies | 34% ± 19% | |
| Schwann cell | 3 studies | 29% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 20% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 94% | 2014.81 | 2486 / 2642 | 100% | 23.63 | 702 / 705 |
| prostate | 98% | 1970.32 | 240 / 245 | 71% | 3.96 | 357 / 502 |
| thymus | 89% | 760.07 | 583 / 653 | 78% | 4.51 | 474 / 605 |
| breast | 100% | 2897.05 | 458 / 459 | 49% | 4.45 | 552 / 1118 |
| lung | 99% | 2366.14 | 573 / 578 | 38% | 2.07 | 441 / 1155 |
| uterus | 99% | 3256.68 | 169 / 170 | 34% | 2.56 | 154 / 459 |
| bladder | 100% | 2589.14 | 21 / 21 | 22% | 1.52 | 113 / 504 |
| kidney | 38% | 390.18 | 34 / 89 | 83% | 8.98 | 751 / 901 |
| esophagus | 75% | 1874.53 | 1084 / 1445 | 45% | 2.60 | 83 / 183 |
| skin | 61% | 2521.17 | 1108 / 1809 | 52% | 5.22 | 247 / 472 |
| ovary | 100% | 2174.44 | 180 / 180 | 10% | 0.40 | 41 / 430 |
| intestine | 82% | 2657.03 | 796 / 966 | 25% | 1.52 | 134 / 527 |
| adipose | 100% | 3353.65 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2926.20 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| stomach | 56% | 1572.52 | 200 / 359 | 31% | 1.85 | 90 / 286 |
| adrenal gland | 19% | 113.63 | 49 / 258 | 61% | 4.52 | 141 / 230 |
| heart | 80% | 756.20 | 690 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 2% | 8.93 | 6 / 328 | 66% | 4.64 | 117 / 178 |
| tonsil | 0% | 0 | 0 / 0 | 44% | 2.93 | 20 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 34% | 1.70 | 10 / 29 |
| liver | 4% | 34.92 | 9 / 226 | 23% | 1.79 | 95 / 406 |
| muscle | 9% | 57.21 | 75 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 6% | 40.22 | 56 / 929 | 0% | 0 | 0 / 0 |
| spleen | 3% | 14.78 | 7 / 241 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.10 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0002052 | Biological process | positive regulation of neuroblast proliferation |
| GO_0006366 | Biological process | transcription by RNA polymerase II |
| GO_2000546 | Biological process | positive regulation of endothelial cell chemotaxis to fibroblast growth factor |
| GO_0001658 | Biological process | branching involved in ureteric bud morphogenesis |
| GO_0030324 | Biological process | lung development |
| GO_1902748 | Biological process | positive regulation of lens fiber cell differentiation |
| GO_0001759 | Biological process | organ induction |
| GO_0071260 | Biological process | cellular response to mechanical stimulus |
| GO_0050918 | Biological process | positive chemotaxis |
| GO_0042491 | Biological process | inner ear auditory receptor cell differentiation |
| GO_0038001 | Biological process | paracrine signaling |
| GO_1905564 | Biological process | positive regulation of vascular endothelial cell proliferation |
| GO_0009792 | Biological process | embryo development ending in birth or egg hatching |
| GO_0006935 | Biological process | chemotaxis |
| GO_1903672 | Biological process | positive regulation of sprouting angiogenesis |
| GO_0060128 | Biological process | corticotropin hormone secreting cell differentiation |
| GO_0060978 | Biological process | angiogenesis involved in coronary vascular morphogenesis |
| GO_0043537 | Biological process | negative regulation of blood vessel endothelial cell migration |
| GO_2000647 | Biological process | negative regulation of stem cell proliferation |
| GO_0030334 | Biological process | regulation of cell migration |
| GO_1902895 | Biological process | positive regulation of miRNA transcription |
| GO_0043491 | Biological process | phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0051897 | Biological process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
| GO_1904707 | Biological process | positive regulation of vascular associated smooth muscle cell proliferation |
| GO_0051726 | Biological process | regulation of cell cycle |
| GO_0072089 | Biological process | stem cell proliferation |
| GO_0045609 | Biological process | positive regulation of inner ear auditory receptor cell differentiation |
| GO_1904977 | Biological process | lymphatic endothelial cell migration |
| GO_0051781 | Biological process | positive regulation of cell division |
| GO_0061045 | Biological process | negative regulation of wound healing |
| GO_0010629 | Biological process | negative regulation of gene expression |
| GO_0046668 | Biological process | regulation of retinal cell programmed cell death |
| GO_0045766 | Biological process | positive regulation of angiogenesis |
| GO_0001649 | Biological process | osteoblast differentiation |
| GO_0007165 | Biological process | signal transduction |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0030214 | Biological process | hyaluronan catabolic process |
| GO_0045669 | Biological process | positive regulation of osteoblast differentiation |
| GO_0045765 | Biological process | regulation of angiogenesis |
| GO_0042060 | Biological process | wound healing |
| GO_0090050 | Biological process | positive regulation of cell migration involved in sprouting angiogenesis |
| GO_0070371 | Biological process | ERK1 and ERK2 cascade |
| GO_2000573 | Biological process | positive regulation of DNA biosynthetic process |
| GO_0060644 | Biological process | mammary gland epithelial cell differentiation |
| GO_2000544 | Biological process | regulation of endothelial cell chemotaxis to fibroblast growth factor |
| GO_0040037 | Biological process | negative regulation of fibroblast growth factor receptor signaling pathway |
| GO_0007399 | Biological process | nervous system development |
| GO_0008543 | Biological process | fibroblast growth factor receptor signaling pathway |
| GO_0007405 | Biological process | neuroblast proliferation |
| GO_0007265 | Biological process | Ras protein signal transduction |
| GO_0090263 | Biological process | positive regulation of canonical Wnt signaling pathway |
| GO_0043536 | Biological process | positive regulation of blood vessel endothelial cell migration |
| GO_0060045 | Biological process | positive regulation of cardiac muscle cell proliferation |
| GO_0009887 | Biological process | animal organ morphogenesis |
| GO_0010001 | Biological process | glial cell differentiation |
| GO_0014843 | Biological process | growth factor dependent regulation of skeletal muscle satellite cell proliferation |
| GO_0043406 | Biological process | positive regulation of MAP kinase activity |
| GO_1905278 | Biological process | positive regulation of epithelial tube formation |
| GO_0048598 | Biological process | embryonic morphogenesis |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0021930 | Biological process | cerebellar granule cell precursor proliferation |
| GO_0060129 | Biological process | thyroid-stimulating hormone-secreting cell differentiation |
| GO_2001028 | Biological process | positive regulation of endothelial cell chemotaxis |
| GO_0090049 | Biological process | regulation of cell migration involved in sprouting angiogenesis |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0060591 | Biological process | chondroblast differentiation |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0002042 | Biological process | cell migration involved in sprouting angiogenesis |
| GO_0010595 | Biological process | positive regulation of endothelial cell migration |
| GO_0048678 | Biological process | response to axon injury |
| GO_2000648 | Biological process | positive regulation of stem cell proliferation |
| GO_1903587 | Biological process | regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis |
| GO_0048864 | Biological process | stem cell development |
| GO_0043410 | Biological process | positive regulation of MAPK cascade |
| GO_0051209 | Biological process | release of sequestered calcium ion into cytosol |
| GO_0010764 | Biological process | negative regulation of fibroblast migration |
| GO_0060070 | Biological process | canonical Wnt signaling pathway |
| GO_0001938 | Biological process | positive regulation of endothelial cell proliferation |
| GO_0030154 | Biological process | cell differentiation |
| GO_0001935 | Biological process | endothelial cell proliferation |
| GO_0021940 | Biological process | positive regulation of cerebellar granule cell precursor proliferation |
| GO_0021762 | Biological process | substantia nigra development |
| GO_0042660 | Biological process | positive regulation of cell fate specification |
| GO_1902913 | Biological process | positive regulation of neuroepithelial cell differentiation |
| GO_2000738 | Biological process | positive regulation of stem cell differentiation |
| GO_0005634 | Cellular component | nucleus |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0090722 | Molecular function | receptor-receptor interaction |
| GO_0042056 | Molecular function | chemoattractant activity |
| GO_0030374 | Molecular function | nuclear receptor coactivator activity |
| GO_0005125 | Molecular function | cytokine activity |
| GO_0008201 | Molecular function | heparin binding |
| GO_0019956 | Molecular function | chemokine binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0008083 | Molecular function | growth factor activity |
| GO_0005178 | Molecular function | integrin binding |
| GO_0005104 | Molecular function | fibroblast growth factor receptor binding |
| Gene name | FGF2 |
| Protein name | Fibroblast growth factor (FGF) Fibroblast growth factor 2 (FGF-2) (Basic fibroblast growth factor) (bFGF) (Heparin-binding growth factor 2) (HBGF-2) |
| Synonyms | FGF2A FGFB |
| Description | FUNCTION: Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 . Also acts as an integrin ligand which is required for FGF2 signaling . Binds to integrin ITGAV:ITGB3 . Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration . Functions as a potent mitogen in vitro . Can induce angiogenesis . Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation . . |
| Accessions | D9ZGF5 ENST00000644866.2 [P09038-2] ENST00000264498.9 [P09038-4] ENST00000264498 P09038 ENST00000608478.1 [P09038-2] A0A0A0MQV6 |
