PLEKHA1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	28 studies	28% ± 12%	Explore
natural killer cell	17 studies	19% ± 4%	Explore
oligodendrocyte	14 studies	38% ± 15%	Explore
capillary endothelial cell	13 studies	20% ± 4%	Explore
type I pneumocyte	11 studies	35% ± 11%	Explore
glutamatergic neuron	10 studies	52% ± 25%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	23% ± 5%	Explore
mature NK T cell	8 studies	19% ± 4%	Explore
basal cell	8 studies	29% ± 16%	Explore
mesothelial cell	7 studies	24% ± 11%	Explore
microglial cell	7 studies	20% ± 5%	Explore
GABAergic neuron	7 studies	47% ± 19%	Explore
macrophage	7 studies	28% ± 6%	Explore
neuron	6 studies	39% ± 12%	Explore
vein endothelial cell	6 studies	23% ± 14%	Explore
epithelial cell	6 studies	47% ± 19%	Explore
fibroblast	6 studies	21% ± 5%	Explore
oligodendrocyte precursor cell	6 studies	25% ± 10%	Explore
endothelial cell of artery	5 studies	22% ± 8%	Explore
endothelial cell of vascular tree	5 studies	25% ± 12%	Explore
interneuron	5 studies	45% ± 21%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	21% ± 5%	Explore
epithelial cell of proximal tubule	4 studies	23% ± 4%	Explore
pericyte	4 studies	20% ± 2%	Explore
myeloid cell	4 studies	21% ± 4%	Explore
cardiac muscle cell	4 studies	26% ± 2%	Explore
ciliated cell	4 studies	27% ± 11%	Explore
hepatocyte	4 studies	39% ± 26%	Explore
endothelial cell of lymphatic vessel	3 studies	27% ± 9%	Explore
pancreatic A cell	3 studies	40% ± 3%	Explore
CD8-positive, alpha-beta T cell	3 studies	20% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	18% ± 3%	Explore
GABAergic interneuron	3 studies	30% ± 4%	Explore
abnormal cell	3 studies	30% ± 10%	Explore
B cell	3 studies	26% ± 4%	Explore
retinal cone cell	3 studies	23% ± 1%	Explore
lymphocyte	3 studies	20% ± 2%	Explore
astrocyte	3 studies	30% ± 6%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	15 studies	36% ± 22%	Explore
lung	5 studies	21% ± 5%	Explore
eye	5 studies	24% ± 9%	Explore
pancreas	3 studies	36% ± 6%	Explore
kidney	3 studies	20% ± 5%	Explore
heart	3 studies	18% ± 2%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4293.75	1445 / 1445	100%	14.26	183 / 183
lung	100%	4457.84	578 / 578	100%	10.74	1150 / 1155
kidney	100%	6249.87	89 / 89	99%	18.12	895 / 901
intestine	100%	3531.30	966 / 966	98%	8.27	515 / 527
stomach	100%	2166.21	358 / 359	98%	9.24	279 / 286
pancreas	99%	2151.66	324 / 328	98%	8.91	175 / 178
uterus	100%	3620.48	170 / 170	97%	9.11	445 / 459
breast	100%	2762.99	459 / 459	97%	6.40	1082 / 1118
bladder	100%	2536.67	21 / 21	96%	7.31	484 / 504
ovary	100%	3169.46	180 / 180	95%	5.42	409 / 430
thymus	100%	3216.87	653 / 653	94%	5.67	571 / 605
prostate	100%	2530.39	245 / 245	91%	4.11	455 / 502
brain	99%	3588.08	2623 / 2642	90%	4.03	635 / 705
adrenal gland	99%	1340.39	255 / 258	89%	4.99	205 / 230
liver	100%	3143.27	226 / 226	87%	4.83	355 / 406
skin	100%	5786.92	1809 / 1809	75%	3.20	353 / 472
adipose	100%	3114.81	1204 / 1204	0%	0	0 / 0
spleen	100%	1803.96	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	9.74	45 / 45
ureter	0%	0	0 / 0	100%	7.82	1 / 1
blood vessel	100%	2974.18	1332 / 1335	0%	0	0 / 0
muscle	100%	3217.19	801 / 803	0%	0	0 / 0
heart	99%	2420.62	852 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	43%	2.50	34 / 80
peripheral blood	27%	294.68	250 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	17%	0.47	5 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0