PIK3C2B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0009267Biological processcellular response to starvation
GO_0008150Biological processbiological_process
GO_0048015Biological processphosphatidylinositol-mediated signaling
GO_1905037Biological processautophagosome organization
GO_0036092Biological processphosphatidylinositol-3-phosphate biosynthetic process
GO_0043491Biological processphosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0016477Biological processcell migration
GO_0005886Cellular componentplasma membrane
GO_0005942Cellular componentphosphatidylinositol 3-kinase complex
GO_0030139Cellular componentendocytic vesicle
GO_0005654Cellular componentnucleoplasm
GO_0005783Cellular componentendoplasmic reticulum
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0035091Molecular functionphosphatidylinositol binding
GO_0005524Molecular functionATP binding
GO_0016303Molecular function1-phosphatidylinositol-3-kinase activity
GO_0035005Molecular function1-phosphatidylinositol-4-phosphate 3-kinase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePIK3C2B
Protein namePhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.137) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta)
PIK3C2B variant protein
PIK3C2B protein
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta (Phosphoinositide-3-kinase, class 2, beta polypeptide)
SynonymshCG_16410
protein
variant
DescriptionFUNCTION: Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns . Does not phosphorylate PtdIns(4,5)P2 . May be involved in EGF and PDGF signaling cascades . .

AccessionsB7ZM86
ENST00000367187.7
ENST00000684373.1
F5GWN5
Q5SW97
ENST00000424712.6
Q5SW98
ENST00000415899.2
O00750
A2RUF7
Q4LE65
Q5SWA0
ENST00000429009.1
ENST00000367184.2