TFDP2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	27 studies	29% ± 8%	Explore
endothelial cell	16 studies	29% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	33% ± 6%	Explore
fibroblast	15 studies	26% ± 9%	Explore
astrocyte	13 studies	35% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	21% ± 4%	Explore
oligodendrocyte	12 studies	30% ± 13%	Explore
oligodendrocyte precursor cell	12 studies	33% ± 12%	Explore
GABAergic neuron	11 studies	49% ± 25%	Explore
glutamatergic neuron	11 studies	52% ± 25%	Explore
ciliated cell	11 studies	26% ± 10%	Explore
mature NK T cell	10 studies	22% ± 6%	Explore
epithelial cell	10 studies	34% ± 18%	Explore
adipocyte	9 studies	41% ± 14%	Explore
basal cell	8 studies	32% ± 15%	Explore
smooth muscle cell	8 studies	22% ± 3%	Explore
neuron	7 studies	39% ± 13%	Explore
hematopoietic stem cell	7 studies	34% ± 11%	Explore
kidney loop of Henle epithelial cell	6 studies	20% ± 4%	Explore
progenitor cell	6 studies	33% ± 15%	Explore
connective tissue cell	6 studies	20% ± 3%	Explore
mesothelial cell	6 studies	24% ± 9%	Explore
interneuron	6 studies	62% ± 17%	Explore
macrophage	6 studies	26% ± 8%	Explore
retinal ganglion cell	6 studies	35% ± 16%	Explore
mast cell	6 studies	24% ± 7%	Explore
type I pneumocyte	6 studies	27% ± 6%	Explore
pericyte	6 studies	20% ± 4%	Explore
hematopoietic precursor cell	5 studies	39% ± 18%	Explore
CD8-positive, alpha-beta T cell	5 studies	26% ± 6%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	25% ± 5%	Explore
T cell	5 studies	28% ± 12%	Explore
precursor B cell	5 studies	37% ± 8%	Explore
myofibroblast cell	5 studies	27% ± 9%	Explore
amacrine cell	5 studies	34% ± 11%	Explore
retina horizontal cell	5 studies	27% ± 7%	Explore
cardiac muscle cell	5 studies	38% ± 9%	Explore
Mueller cell	5 studies	23% ± 9%	Explore
endothelial cell of lymphatic vessel	5 studies	21% ± 4%	Explore
club cell	5 studies	30% ± 10%	Explore
type II pneumocyte	5 studies	22% ± 7%	Explore
gamma-delta T cell	5 studies	31% ± 24%	Explore
granule cell	4 studies	40% ± 7%	Explore
microglial cell	4 studies	29% ± 9%	Explore
B cell	4 studies	21% ± 3%	Explore
lymphocyte	4 studies	23% ± 5%	Explore
retinal cone cell	4 studies	22% ± 5%	Explore
retinal rod cell	4 studies	22% ± 5%	Explore
respiratory goblet cell	4 studies	26% ± 12%	Explore
erythrocyte	4 studies	43% ± 22%	Explore
renal principal cell	4 studies	22% ± 4%	Explore
secretory cell	3 studies	22% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	18% ± 2%	Explore
epithelial cell of proximal tubule	3 studies	33% ± 5%	Explore
neural crest cell	3 studies	42% ± 3%	Explore
GABAergic interneuron	3 studies	46% ± 4%	Explore
glial cell	3 studies	37% ± 15%	Explore
placental villous trophoblast	3 studies	47% ± 18%	Explore
pro-B cell	3 studies	26% ± 3%	Explore
myeloid cell	3 studies	16% ± 1%	Explore
GABAergic amacrine cell	3 studies	38% ± 7%	Explore
OFF-bipolar cell	3 studies	31% ± 4%	Explore
ON-bipolar cell	3 studies	28% ± 3%	Explore
glycinergic amacrine cell	3 studies	37% ± 1%	Explore
hepatocyte	3 studies	43% ± 14%	Explore
dendritic cell	3 studies	28% ± 4%	Explore
abnormal cell	3 studies	29% ± 15%	Explore
ependymal cell	3 studies	35% ± 12%	Explore
enteroendocrine cell	3 studies	29% ± 10%	Explore
intestinal crypt stem cell	3 studies	20% ± 3%	Explore
adventitial cell	3 studies	19% ± 5%	Explore
transit amplifying cell	3 studies	43% ± 30%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	23% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	16 studies	41% ± 20%	Explore
lung	6 studies	23% ± 5%	Explore
eye	5 studies	35% ± 12%	Explore
heart	4 studies	25% ± 4%	Explore
liver	4 studies	38% ± 16%	Explore
intestine	4 studies	20% ± 4%	Explore
peripheral blood	3 studies	22% ± 3%	Explore
placenta	3 studies	22% ± 8%	Explore
bone marrow	3 studies	19% ± 4%	Explore
adipose	3 studies	30% ± 4%	Explore
kidney	3 studies	28% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	4818.06	180 / 180	100%	22.69	430 / 430
prostate	100%	3779.45	245 / 245	100%	23.08	502 / 502
thymus	100%	3082.13	653 / 653	100%	35.30	604 / 605
intestine	100%	3522.72	966 / 966	100%	13.84	526 / 527
breast	100%	3215.82	459 / 459	100%	16.75	1115 / 1118
uterus	100%	3497.62	170 / 170	100%	18.21	457 / 459
brain	99%	1970.82	2628 / 2642	100%	19.88	705 / 705
stomach	100%	2700.54	359 / 359	99%	16.60	284 / 286
bladder	100%	3006.33	21 / 21	99%	13.00	499 / 504
esophagus	100%	2917.34	1444 / 1445	99%	19.33	181 / 183
adrenal gland	100%	3469.04	258 / 258	99%	13.37	227 / 230
kidney	100%	2880.70	89 / 89	98%	16.15	887 / 901
lung	99%	1867.65	573 / 578	99%	16.34	1146 / 1155
pancreas	98%	1205.57	320 / 328	98%	10.52	175 / 178
skin	100%	2648.68	1809 / 1809	93%	11.80	440 / 472
liver	96%	1085.17	217 / 226	91%	7.00	371 / 406
adipose	100%	2878.30	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2929.69	1335 / 1335	0%	0	0 / 0
spleen	100%	1608.20	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	22.90	45 / 45
ureter	0%	0	0 / 0	100%	7.74	1 / 1
muscle	100%	2444.90	801 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	9.04	28 / 29
heart	96%	2347.57	828 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	79%	6.50	63 / 80
peripheral blood	74%	1350.32	688 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0051726	Biological process	regulation of cell cycle
GO_0007507	Biological process	heart development
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0072686	Cellular component	mitotic spindle
GO_0090575	Cellular component	RNA polymerase II transcription regulator complex
GO_0005654	Cellular component	nucleoplasm
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0008134	Molecular function	transcription factor binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0001228	Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977	Molecular function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0019904	Molecular function	protein domain specific binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	TFDP2
Protein name	Transcription factor Dp-2 (E2F dimerization partner 2) Transcription factor Dp-2
Synonyms	DP2
Description	FUNCTION: Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters . .
Accessions	ENST00000479040.5 [Q14188-4] C9J977 ENST00000478006.5 C9J872 F8WAY9 ENST00000487734.5 ENST00000488107.6 ENST00000467634.1 ENST00000467667.5 ENST00000486111.5 [Q14188-5] ENST00000497579.5 R4GN09 ENST00000494656.3 C9JTZ9 C9J5D5 ENST00000499676.5 [Q14188-8] ENST00000495310.5 [Q14188-6] ENST00000475734.5 C9JNB6 ENST00000467072.5 [Q14188-5] C9JCY5 Q14188 ENST00000477292.5 [Q14188-7] ENST00000489671.6 [Q14188-1] H7C5C2 C9J461 ENST00000494358.5 ENST00000474279.3

TFDP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review