OXT | OmnibusX

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of OXT at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	99%	168.87	223 / 226	35%	5.97	144 / 406
kidney	97%	42.78	86 / 89	28%	1.66	253 / 901
breast	98%	33.66	450 / 459	21%	0.42	237 / 1118
thymus	93%	14.59	606 / 653	23%	0.45	139 / 605
uterus	86%	10.84	146 / 170	26%	0.76	121 / 459
esophagus	58%	5.27	837 / 1445	48%	1.53	88 / 183
adrenal gland	93%	29.55	239 / 258	12%	0.90	27 / 230
ureter	0%	0	0 / 0	100%	3.13	1 / 1
ovary	52%	6.81	93 / 180	43%	1.11	185 / 430
adipose	94%	41.57	1136 / 1204	0%	0	0 / 0
prostate	90%	15.90	221 / 245	4%	0.07	19 / 502
intestine	68%	9.07	661 / 966	21%	0.70	109 / 527
skin	79%	23.48	1433 / 1809	9%	0.32	41 / 472
bladder	71%	9.67	15 / 21	15%	0.32	75 / 504
brain	80%	3674.28	2120 / 2642	2%	0.04	17 / 705
stomach	40%	3.33	142 / 359	40%	1.78	114 / 286
lung	46%	4.12	266 / 578	24%	1.03	282 / 1155
heart	66%	6.49	568 / 861	0%	0	0 / 0
spleen	64%	5.32	154 / 241	0%	0	0 / 0
pancreas	16%	1.37	52 / 328	32%	0.67	57 / 178
peripheral blood	44%	4.16	407 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	40%	0.89	18 / 45
blood vessel	34%	2.58	453 / 1335	0%	0	0 / 0
muscle	26%	2.06	205 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	15%	0.35	12 / 80
lymph node	0%	0	0 / 0	7%	0.21	2 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0042756	Biological process	drinking behavior
GO_0032355	Biological process	response to estradiol
GO_0007625	Biological process	grooming behavior
GO_0060450	Biological process	positive regulation of hindgut contraction
GO_0060406	Biological process	positive regulation of penile erection
GO_0043434	Biological process	response to peptide hormone
GO_0045777	Biological process	positive regulation of blood pressure
GO_0045925	Biological process	positive regulation of female receptivity
GO_0007507	Biological process	heart development
GO_0051602	Biological process	response to electrical stimulus
GO_0007165	Biological process	signal transduction
GO_0060179	Biological process	male mating behavior
GO_0002027	Biological process	regulation of heart rate
GO_0042713	Biological process	sperm ejaculation
GO_0014823	Biological process	response to activity
GO_0007565	Biological process	female pregnancy
GO_0035811	Biological process	negative regulation of urine volume
GO_0002125	Biological process	maternal aggressive behavior
GO_0042220	Biological process	response to cocaine
GO_0051591	Biological process	response to cAMP
GO_0042711	Biological process	maternal behavior
GO_0051384	Biological process	response to glucocorticoid
GO_0045776	Biological process	negative regulation of blood pressure
GO_0007204	Biological process	positive regulation of cytosolic calcium ion concentration
GO_0009744	Biological process	response to sucrose
GO_0010701	Biological process	positive regulation of norepinephrine secretion
GO_0070474	Biological process	positive regulation of uterine smooth muscle contraction
GO_0042755	Biological process	eating behavior
GO_0034695	Biological process	response to prostaglandin E
GO_0120162	Biological process	positive regulation of cold-induced thermogenesis
GO_0007613	Biological process	memory
GO_0032308	Biological process	positive regulation of prostaglandin secretion
GO_0032526	Biological process	response to retinoic acid
GO_0001975	Biological process	response to amphetamine
GO_0050806	Biological process	positive regulation of synaptic transmission
GO_0045472	Biological process	response to ether
GO_0032094	Biological process	response to food
GO_0035176	Biological process	social behavior
GO_0045778	Biological process	positive regulation of ossification
GO_0051965	Biological process	positive regulation of synapse assembly
GO_0032570	Biological process	response to progesterone
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0043195	Cellular component	terminal bouton
GO_0030141	Cellular component	secretory granule
GO_0005185	Molecular function	neurohypophyseal hormone activity
GO_0031855	Molecular function	oxytocin receptor binding
GO_0031894	Molecular function	V1A vasopressin receptor binding
GO_0005515	Molecular function	protein binding
GO_0005184	Molecular function	neuropeptide hormone activity

Gene name	OXT
Protein name	Oxytocin-neurophysin 1 (OT-NPI) [Cleaved into: Oxytocin (Ocytocin); Neurophysin 1] Oxytocin-neurophysin 1
Synonyms	hCG_39619 OT
Description	FUNCTION: Neurophysin 1 specifically binds oxytocin.; FUNCTION: Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. Acts by binding to oxytocin receptor (OXTR) . . FUNCTION: Neurophysin 1 specifically binds oxytocin. .
Accessions	P01178 ENST00000217386.2 X5D7M6

OXT report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review