PDLIM2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0061061Biological processmuscle structure development
GO_0030036Biological processactin cytoskeleton organization
GO_0007507Biological processheart development
GO_0030163Biological processprotein catabolic process
GO_0001725Cellular componentstress fiber
GO_0005912Cellular componentadherens junction
GO_0031941Cellular componentfilamentous actin
GO_0030864Cellular componentcortical actin cytoskeleton
GO_0030018Cellular componentZ disc
GO_0005634Cellular componentnucleus
GO_0032036Molecular functionmyosin heavy chain binding
GO_0051371Molecular functionmuscle alpha-actinin binding
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding
GO_0046872Molecular functionmetal ion binding
GO_0031005Molecular functionfilamin binding

IV. Literature review

[source]
Gene namePDLIM2
Protein namePDZ and LIM domain 2
PDZ and LIM domain 2 (cDNA FLJ32186 fis, clone PLACE6002011, highly similar to PDZ and LIM domain protein 2)
PDZ and LIM domain protein 2 (PDZ-LIM protein mystique)
SynonymsPP6345
DescriptionFUNCTION: Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity. .

AccessionsENST00000452226.5
F8WFB8
ENST00000409141.5 [Q96JY6-4]
ENST00000397760.8 [Q96JY6-1]
ENST00000397761.6 [Q96JY6-1]
A0A087WU48
ENST00000339162.11 [Q96JY6-5]
A0A087WXJ0
C9K0F0
ENST00000448520.5
ENST00000616289.1
ENST00000614502.4
ENST00000409417.6 [Q96JY6-1]
Q96JY6
ENST00000436754.5
ENST00000456545.5
ENST00000308354.11 [Q96JY6-5]
A0A087WUQ1
ENST00000443561.3
C9JSR2
ENST00000265810.8 [Q96JY6-3]
ENST00000426493.5
ENST00000464275.5
C9JS55
C9J0X3
C9J760
ENST00000416159.5
B3KPU0
ENST00000429812.5