PDLIM7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006898Biological processreceptor-mediated endocytosis
GO_0007507Biological processheart development
GO_0061061Biological processmuscle structure development
GO_0030036Biological processactin cytoskeleton organization
GO_0030154Biological processcell differentiation
GO_0001503Biological processossification
GO_0001726Cellular componentruffle
GO_0031941Cellular componentfilamentous actin
GO_0030018Cellular componentZ disc
GO_0005654Cellular componentnucleoplasm
GO_0005925Cellular componentfocal adhesion
GO_0001725Cellular componentstress fiber
GO_0015629Cellular componentactin cytoskeleton
GO_0005829Cellular componentcytosol
GO_0005912Cellular componentadherens junction
GO_0051371Molecular functionmuscle alpha-actinin binding
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene namePDLIM7
Protein namePDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)
PDZ and LIM domain 7
SynonymsENIGMA
DescriptionFUNCTION: May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity). .

AccessionsENST00000355841.7 [Q9NR12-1]
ENST00000506537.1
Q9NR12
ENST00000486828.6 [Q9NR12-5]
D6RAN1
ENST00000359895.6 [Q9NR12-2]
H7BYK4
D6RF83
D6RH06
ENST00000493815.5 [Q9NR12-3]
ENST00000355572.6 [Q9NR12-6]
ENST00000393546.8
ENST00000393551.5 [Q9NR12-4]
ENST00000506161.5
ENST00000505074.5