Name | Number of supported studies | Average coverage | |
---|---|---|---|
smooth muscle cell | 28 studies | 48% ± 23% | |
pericyte | 21 studies | 35% ± 13% | |
fibroblast | 20 studies | 31% ± 12% | |
myofibroblast cell | 15 studies | 51% ± 19% | |
endothelial cell | 12 studies | 24% ± 10% | |
connective tissue cell | 10 studies | 38% ± 15% | |
classical monocyte | 5 studies | 26% ± 4% | |
megakaryocyte | 5 studies | 54% ± 26% | |
endothelial cell of artery | 4 studies | 23% ± 6% | |
vein endothelial cell | 4 studies | 24% ± 7% | |
platelet | 4 studies | 24% ± 8% | |
myoepithelial cell | 4 studies | 34% ± 6% | |
neutrophil | 3 studies | 22% ± 3% | |
non-classical monocyte | 3 studies | 20% ± 4% | |
epithelial cell | 3 studies | 20% ± 3% | |
endothelial cell of vascular tree | 3 studies | 18% ± 1% | |
muscle cell | 3 studies | 51% ± 24% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
uterus | 99% | 35980.06 | 168 / 170 | 100% | 98.24 | 458 / 459 |
prostate | 99% | 24268.75 | 243 / 245 | 98% | 66.94 | 494 / 502 |
bladder | 100% | 27958.90 | 21 / 21 | 95% | 53.42 | 480 / 504 |
ovary | 95% | 8510.10 | 171 / 180 | 100% | 78.95 | 429 / 430 |
lung | 95% | 7839.79 | 547 / 578 | 97% | 51.88 | 1125 / 1155 |
esophagus | 87% | 23449.22 | 1258 / 1445 | 100% | 66.85 | 183 / 183 |
breast | 81% | 5327.75 | 373 / 459 | 97% | 47.13 | 1090 / 1118 |
intestine | 82% | 29057.59 | 795 / 966 | 96% | 46.24 | 508 / 527 |
stomach | 56% | 11372.31 | 201 / 359 | 97% | 57.83 | 278 / 286 |
skin | 50% | 3938.34 | 909 / 1809 | 98% | 45.75 | 463 / 472 |
thymus | 49% | 2559.63 | 317 / 653 | 98% | 46.43 | 590 / 605 |
kidney | 54% | 3405.92 | 48 / 89 | 88% | 30.15 | 794 / 901 |
adrenal gland | 14% | 692.35 | 37 / 258 | 87% | 30.79 | 200 / 230 |
lymph node | 0% | 0 | 0 / 0 | 100% | 37.45 | 29 / 29 |
tonsil | 0% | 0 | 0 / 0 | 100% | 47.69 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 40.36 | 1 / 1 |
blood vessel | 100% | 37294.20 | 1334 / 1335 | 0% | 0 | 0 / 0 |
pancreas | 1% | 68.90 | 3 / 328 | 98% | 119.29 | 174 / 178 |
spleen | 98% | 8175.43 | 235 / 241 | 0% | 0 | 0 / 0 |
muscle | 96% | 9928.99 | 771 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 78% | 10036.70 | 727 / 929 | 0% | 0 | 0 / 0 |
adipose | 77% | 5730.55 | 925 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 75% | 16.29 | 60 / 80 |
brain | 3% | 144.52 | 88 / 2642 | 68% | 20.44 | 482 / 705 |
liver | 1% | 86.99 | 3 / 226 | 53% | 16.91 | 214 / 406 |
heart | 48% | 2887.93 | 415 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006898 | Biological process | receptor-mediated endocytosis |
GO_0007507 | Biological process | heart development |
GO_0061061 | Biological process | muscle structure development |
GO_0030036 | Biological process | actin cytoskeleton organization |
GO_0030154 | Biological process | cell differentiation |
GO_0001503 | Biological process | ossification |
GO_0001726 | Cellular component | ruffle |
GO_0031941 | Cellular component | filamentous actin |
GO_0030018 | Cellular component | Z disc |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005925 | Cellular component | focal adhesion |
GO_0001725 | Cellular component | stress fiber |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005912 | Cellular component | adherens junction |
GO_0051371 | Molecular function | muscle alpha-actinin binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0003779 | Molecular function | actin binding |
Gene name | PDLIM7 |
Protein name | PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma) PDZ and LIM domain 7 |
Synonyms | ENIGMA |
Description | FUNCTION: May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity). . |
Accessions | ENST00000355841.7 [Q9NR12-1] ENST00000506537.1 Q9NR12 ENST00000486828.6 [Q9NR12-5] D6RAN1 ENST00000359895.6 [Q9NR12-2] H7BYK4 D6RF83 D6RH06 ENST00000493815.5 [Q9NR12-3] ENST00000355572.6 [Q9NR12-6] ENST00000393546.8 ENST00000393551.5 [Q9NR12-4] ENST00000506161.5 ENST00000505074.5 |