Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 19 studies | 41% ± 14% | |
astrocyte | 16 studies | 37% ± 17% | |
fibroblast | 15 studies | 52% ± 19% | |
oligodendrocyte precursor cell | 14 studies | 68% ± 20% | |
glutamatergic neuron | 12 studies | 61% ± 21% | |
pericyte | 12 studies | 39% ± 16% | |
smooth muscle cell | 11 studies | 39% ± 17% | |
adipocyte | 10 studies | 55% ± 20% | |
endothelial cell of lymphatic vessel | 9 studies | 66% ± 23% | |
GABAergic neuron | 7 studies | 49% ± 17% | |
mesothelial cell | 7 studies | 57% ± 22% | |
cardiac muscle cell | 6 studies | 68% ± 21% | |
neuron | 4 studies | 44% ± 24% | |
granule cell | 4 studies | 75% ± 20% | |
interneuron | 4 studies | 66% ± 19% | |
vein endothelial cell | 4 studies | 51% ± 26% | |
retina horizontal cell | 4 studies | 27% ± 8% | |
oligodendrocyte | 4 studies | 38% ± 27% | |
microglial cell | 3 studies | 53% ± 25% | |
progenitor cell | 3 studies | 41% ± 15% | |
GABAergic amacrine cell | 3 studies | 50% ± 14% | |
glycinergic amacrine cell | 3 studies | 53% ± 15% | |
endothelial cell of vascular tree | 3 studies | 40% ± 13% | |
ependymal cell | 3 studies | 28% ± 12% | |
mast cell | 3 studies | 29% ± 9% | |
capillary endothelial cell | 3 studies | 39% ± 6% | |
myofibroblast cell | 3 studies | 51% ± 25% | |
type I pneumocyte | 3 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 4381.29 | 180 / 180 | 84% | 5.21 | 362 / 430 |
brain | 90% | 1494.45 | 2388 / 2642 | 91% | 9.38 | 645 / 705 |
breast | 100% | 1085.48 | 457 / 459 | 82% | 3.15 | 914 / 1118 |
lung | 99% | 832.54 | 570 / 578 | 75% | 2.47 | 872 / 1155 |
thymus | 100% | 1455.11 | 651 / 653 | 70% | 2.56 | 426 / 605 |
esophagus | 81% | 936.62 | 1165 / 1445 | 67% | 2.16 | 122 / 183 |
adrenal gland | 83% | 379.74 | 215 / 258 | 61% | 2.78 | 140 / 230 |
bladder | 100% | 1570.33 | 21 / 21 | 41% | 1.07 | 208 / 504 |
uterus | 99% | 2358.78 | 168 / 170 | 42% | 1.55 | 191 / 459 |
intestine | 81% | 671.24 | 785 / 966 | 33% | 0.97 | 175 / 527 |
kidney | 38% | 156.69 | 34 / 89 | 67% | 1.96 | 600 / 901 |
adipose | 100% | 2116.35 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1615.27 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 1508.78 | 802 / 803 | 0% | 0 | 0 / 0 |
skin | 53% | 212.07 | 956 / 1809 | 43% | 1.32 | 205 / 472 |
heart | 95% | 1225.92 | 822 / 861 | 0% | 0 | 0 / 0 |
stomach | 52% | 506.44 | 188 / 359 | 42% | 1.31 | 121 / 286 |
spleen | 86% | 400.61 | 208 / 241 | 0% | 0 | 0 / 0 |
pancreas | 2% | 6.93 | 8 / 328 | 83% | 3.31 | 147 / 178 |
tonsil | 0% | 0 | 0 / 0 | 56% | 1.70 | 25 / 45 |
liver | 34% | 120.19 | 76 / 226 | 21% | 0.42 | 84 / 406 |
prostate | 28% | 144.07 | 68 / 245 | 10% | 0.18 | 48 / 502 |
lymph node | 0% | 0 | 0 / 0 | 31% | 0.50 | 9 / 29 |
eye | 0% | 0 | 0 / 0 | 3% | 0.03 | 2 / 80 |
peripheral blood | 0% | 0.74 | 2 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007506 | Biological process | gonadal mesoderm development |
GO_2000195 | Biological process | negative regulation of female gonad development |
GO_0030324 | Biological process | lung development |
GO_0048568 | Biological process | embryonic organ development |
GO_0003148 | Biological process | outflow tract septum morphogenesis |
GO_0001701 | Biological process | in utero embryonic development |
GO_0060045 | Biological process | positive regulation of cardiac muscle cell proliferation |
GO_0007507 | Biological process | heart development |
GO_0045599 | Biological process | negative regulation of fat cell differentiation |
GO_0001570 | Biological process | vasculogenesis |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0030154 | Biological process | cell differentiation |
GO_0003221 | Biological process | right ventricular cardiac muscle tissue morphogenesis |
GO_0060412 | Biological process | ventricular septum morphogenesis |
GO_2000020 | Biological process | positive regulation of male gonad development |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0045444 | Biological process | fat cell differentiation |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005737 | Cellular component | cytoplasm |
GO_0001673 | Cellular component | male germ cell nucleus |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0003714 | Molecular function | transcription corepressor activity |
GO_0061629 | Molecular function | RNA polymerase II-specific DNA-binding transcription factor binding |
GO_0008270 | Molecular function | zinc ion binding |
GO_0003713 | Molecular function | transcription coactivator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ZFPM2 |
Protein name | Zinc finger protein ZFPM2 (Friend of GATA protein 2) (FOG-2) (Friend of GATA 2) (hFOG-2) (Zinc finger protein 89B) (Zinc finger protein multitype 2) Zinc finger protein, FOG family member 2 Zinc finger protein, multitype 2 |
Synonyms | ZNF89B FOG2 |
Description | FUNCTION: Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY. Probably acts a corepressor of NR2F2 (By similarity). . |
Accessions | ENST00000517361.1 ENST00000407775.7 [Q8WW38-1] ENST00000520492.5 E5RJX0 E7ET52 Q8WW38 Q32MA5 ENST00000520027.5 |