I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 3 studies | 18% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 3 studies | 18% ± 2% |
Insufficient scRNA-seq data for expression of OXTR at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 659.02 | 2626 / 2642 | 95% | 14.17 | 669 / 705 |
| ovary | 91% | 211.77 | 163 / 180 | 92% | 21.10 | 395 / 430 |
| breast | 67% | 3977.95 | 308 / 459 | 93% | 11.76 | 1035 / 1118 |
| prostate | 90% | 180.04 | 220 / 245 | 60% | 1.41 | 303 / 502 |
| uterus | 68% | 266.73 | 115 / 170 | 62% | 2.65 | 285 / 459 |
| kidney | 55% | 62.89 | 49 / 89 | 61% | 3.00 | 549 / 901 |
| lung | 60% | 102.88 | 345 / 578 | 49% | 1.84 | 562 / 1155 |
| esophagus | 54% | 146.57 | 779 / 1445 | 54% | 1.90 | 98 / 183 |
| thymus | 56% | 47.25 | 363 / 653 | 45% | 1.26 | 271 / 605 |
| intestine | 33% | 31.84 | 321 / 966 | 64% | 1.76 | 338 / 527 |
| pancreas | 5% | 5.13 | 17 / 328 | 85% | 4.34 | 152 / 178 |
| stomach | 16% | 23.92 | 59 / 359 | 65% | 2.16 | 187 / 286 |
| spleen | 75% | 71.54 | 181 / 241 | 0% | 0 | 0 / 0 |
| adrenal gland | 27% | 22.46 | 70 / 258 | 47% | 1.87 | 107 / 230 |
| bladder | 24% | 19.71 | 5 / 21 | 45% | 2.71 | 229 / 504 |
| skin | 34% | 185.84 | 612 / 1809 | 35% | 1.03 | 164 / 472 |
| blood vessel | 56% | 152.47 | 754 / 1335 | 0% | 0 | 0 / 0 |
| heart | 49% | 45.61 | 423 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 42% | 2.43 | 19 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 34% | 1.44 | 10 / 29 |
| liver | 5% | 4.21 | 12 / 226 | 21% | 3.35 | 85 / 406 |
| peripheral blood | 20% | 382.16 | 186 / 929 | 0% | 0 | 0 / 0 |
| adipose | 16% | 13.98 | 192 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 11% | 8.99 | 91 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 9% | 0.21 | 7 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0044849 | Biological process | estrous cycle |
| GO_0032355 | Biological process | response to estradiol |
| GO_0060406 | Biological process | positive regulation of penile erection |
| GO_0043434 | Biological process | response to peptide hormone |
| GO_0045777 | Biological process | positive regulation of blood pressure |
| GO_0034059 | Biological process | response to anoxia |
| GO_0007507 | Biological process | heart development |
| GO_0034097 | Biological process | response to cytokine |
| GO_0060137 | Biological process | maternal process involved in parturition |
| GO_0045907 | Biological process | positive regulation of vasoconstriction |
| GO_0032870 | Biological process | cellular response to hormone stimulus |
| GO_0006936 | Biological process | muscle contraction |
| GO_0042713 | Biological process | sperm ejaculation |
| GO_0007565 | Biological process | female pregnancy |
| GO_0001992 | Biological process | regulation of systemic arterial blood pressure by vasopressin |
| GO_0001967 | Biological process | suckling behavior |
| GO_0042220 | Biological process | response to cocaine |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0042711 | Biological process | maternal behavior |
| GO_0070371 | Biological process | ERK1 and ERK2 cascade |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0010701 | Biological process | positive regulation of norepinephrine secretion |
| GO_0070474 | Biological process | positive regulation of uterine smooth muscle contraction |
| GO_0042755 | Biological process | eating behavior |
| GO_0120162 | Biological process | positive regulation of cold-induced thermogenesis |
| GO_0048565 | Biological process | digestive tract development |
| GO_0007613 | Biological process | memory |
| GO_0051968 | Biological process | positive regulation of synaptic transmission, glutamatergic |
| GO_0001975 | Biological process | response to amphetamine |
| GO_0007595 | Biological process | lactation |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0032230 | Biological process | positive regulation of synaptic transmission, GABAergic |
| GO_0035176 | Biological process | social behavior |
| GO_0051965 | Biological process | positive regulation of synapse assembly |
| GO_0032570 | Biological process | response to progesterone |
| GO_0021537 | Biological process | telencephalon development |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0005902 | Cellular component | microvillus |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005912 | Cellular component | adherens junction |
| GO_0004990 | Molecular function | oxytocin receptor activity |
| GO_0042277 | Molecular function | peptide binding |
| GO_0017046 | Molecular function | peptide hormone binding |
| GO_0005000 | Molecular function | vasopressin receptor activity |
| Gene name | OXTR |
| Protein name | Oxytocin receptor Alternative protein OXTR Oxytocin receptor isoform A Oxytocin receptor (OT-R) |
| Synonyms | hCG_20370 |
| Description | FUNCTION: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. . FUNCTION: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. FUNCTION: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. . |
| Accessions | ENST00000316793.8 L8E6Y2 C9JQC4 X5DRH4 C9JN09 B2R9L7 P30559 A0T1J2 ENST00000431493.1 ENST00000449615.1 |
