I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 17 studies | 32% ± 13% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 17 studies | 32% ± 13% |
Insufficient scRNA-seq data for expression of DAW1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 92% | 242.17 | 530 / 578 | 35% | 1.90 | 409 / 1155 |
| brain | 68% | 173.53 | 1788 / 2642 | 15% | 0.71 | 104 / 705 |
| kidney | 22% | 9.30 | 20 / 89 | 22% | 0.82 | 195 / 901 |
| skin | 32% | 63.32 | 580 / 1809 | 3% | 0.14 | 12 / 472 |
| ovary | 4% | 1.56 | 7 / 180 | 30% | 1.37 | 131 / 430 |
| blood vessel | 32% | 27.28 | 423 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 31% | 29.46 | 374 / 1204 | 0% | 0 | 0 / 0 |
| heart | 25% | 18.81 | 219 / 861 | 0% | 0 | 0 / 0 |
| thymus | 4% | 2.15 | 29 / 653 | 11% | 0.33 | 69 / 605 |
| bladder | 10% | 8.81 | 2 / 21 | 6% | 0.29 | 31 / 504 |
| uterus | 5% | 24.74 | 8 / 170 | 9% | 0.45 | 40 / 459 |
| tonsil | 0% | 0 | 0 / 0 | 11% | 0.28 | 5 / 45 |
| pancreas | 0% | 0 | 0 / 328 | 11% | 0.42 | 19 / 178 |
| esophagus | 1% | 0.63 | 10 / 1445 | 5% | 0.21 | 10 / 183 |
| breast | 5% | 4.56 | 24 / 459 | 1% | 0.01 | 8 / 1118 |
| stomach | 2% | 0.71 | 6 / 359 | 4% | 0.08 | 11 / 286 |
| intestine | 1% | 0.39 | 11 / 966 | 3% | 0.13 | 14 / 527 |
| prostate | 4% | 2.97 | 9 / 245 | 0% | 0 | 0 / 502 |
| peripheral blood | 2% | 1.92 | 19 / 929 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 258 | 2% | 0.13 | 4 / 230 |
| liver | 1% | 0.39 | 2 / 226 | 1% | 0.01 | 3 / 406 |
| muscle | 0% | 0.49 | 2 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0090660 | Biological process | cerebrospinal fluid circulation |
| GO_0042073 | Biological process | intraciliary transport |
| GO_0000209 | Biological process | protein polyubiquitination |
| GO_0008150 | Biological process | biological_process |
| GO_0036158 | Biological process | outer dynein arm assembly |
| GO_0007507 | Biological process | heart development |
| GO_0007368 | Biological process | determination of left/right symmetry |
| GO_0005575 | Cellular component | cellular_component |
| GO_0019005 | Cellular component | SCF ubiquitin ligase complex |
| GO_0031514 | Cellular component | motile cilium |
| GO_0005929 | Cellular component | cilium |
| GO_0036064 | Cellular component | ciliary basal body |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005737 | Cellular component | cytoplasm |
| GO_1990756 | Molecular function | ubiquitin-like ligase-substrate adaptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | DAW1 |
| Protein name | Dynein assembly factor with WD repeats 1 (WD repeat domain 69, isoform CRA_c) Dynein assembly factor with WD repeats 1 Dynein assembly factor with WD repeat domains 1 (Outer row dynein assembly protein 16 homolog) (WD repeat-containing protein 69) |
| Synonyms | hCG_1776311 WDR69 ODA16 |
| Description | FUNCTION: Required for axonemal dynein assembly and ciliary motility in ciliated organs, including Kupffer's vesicle, during embryogenesis . Facilitates the onset of robust cilia motility during development . . |
| Accessions | ENST00000373666.6 F8WCV0 C9JP90 ENST00000309931.3 [Q8N136-1] ENST00000454999.5 ENST00000440997.1 Q8N136 C9JBF9 |
