MEF2B report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MEF2B at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MEF2B at tissue level.

III. Associated gene sets

GO_0030154Biological processcell differentiation
GO_0007517Biological processmuscle organ development
GO_0007507Biological processheart development
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0030054Cellular componentcell junction
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000785Cellular componentchromatin
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0046983Molecular functionprotein dimerization activity
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0042826Molecular functionhistone deacetylase binding

IV. Literature review

[source]
Gene nameMEF2B
Protein nameMyocyte enhancer factor 2B (cDNA FLJ32648 fis, clone SYNOV2001451, highly similar to MYOCYTE-SPECIFIC ENHANCER FACTOR 2B)
Myocyte-specific enhancer factor 2B (RSRFR2) (Serum response factor-like protein 2)
Myocyte enhancer factor 2B
SynonymsXMEF2
DescriptionFUNCTION: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.

AccessionsENST00000424583.7 [Q02080-2]
ENST00000409447.2
ENST00000410050.5
ENST00000444486.7 [Q02080-1]
ENST00000409224.5
B8ZZJ5
Q02080
B3KQ23
C9J4J4