Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 47 studies | 38% ± 15% | |
smooth muscle cell | 31 studies | 37% ± 16% | |
pericyte | 30 studies | 31% ± 14% | |
fibroblast | 26 studies | 33% ± 19% | |
astrocyte | 20 studies | 48% ± 19% | |
basal cell | 17 studies | 34% ± 14% | |
non-classical monocyte | 16 studies | 27% ± 12% | |
epithelial cell | 15 studies | 38% ± 22% | |
macrophage | 15 studies | 26% ± 9% | |
oligodendrocyte precursor cell | 14 studies | 41% ± 19% | |
endothelial cell of artery | 13 studies | 36% ± 11% | |
vein endothelial cell | 13 studies | 39% ± 16% | |
endothelial cell of vascular tree | 13 studies | 36% ± 15% | |
mast cell | 12 studies | 31% ± 18% | |
ciliated cell | 11 studies | 28% ± 12% | |
capillary endothelial cell | 11 studies | 24% ± 6% | |
secretory cell | 9 studies | 26% ± 8% | |
myeloid cell | 9 studies | 32% ± 16% | |
adipocyte | 9 studies | 44% ± 15% | |
mesothelial cell | 9 studies | 45% ± 14% | |
respiratory goblet cell | 8 studies | 36% ± 14% | |
club cell | 7 studies | 28% ± 13% | |
goblet cell | 7 studies | 33% ± 24% | |
cardiac muscle cell | 7 studies | 83% ± 24% | |
dendritic cell | 7 studies | 27% ± 7% | |
type I pneumocyte | 7 studies | 28% ± 7% | |
hepatocyte | 6 studies | 60% ± 26% | |
abnormal cell | 6 studies | 26% ± 12% | |
endothelial cell of lymphatic vessel | 6 studies | 26% ± 7% | |
monocyte | 6 studies | 29% ± 9% | |
classical monocyte | 5 studies | 24% ± 6% | |
podocyte | 5 studies | 52% ± 24% | |
microglial cell | 5 studies | 29% ± 14% | |
retinal cone cell | 5 studies | 20% ± 4% | |
connective tissue cell | 5 studies | 34% ± 11% | |
oligodendrocyte | 5 studies | 26% ± 10% | |
neuron | 5 studies | 42% ± 12% | |
squamous epithelial cell | 4 studies | 61% ± 16% | |
GABAergic neuron | 4 studies | 27% ± 8% | |
conventional dendritic cell | 4 studies | 20% ± 5% | |
enterocyte | 4 studies | 22% ± 4% | |
retinal pigment epithelial cell | 4 studies | 57% ± 14% | |
Mueller cell | 4 studies | 37% ± 9% | |
luminal hormone-sensing cell of mammary gland | 4 studies | 35% ± 10% | |
luminal cell of prostate epithelium | 4 studies | 41% ± 11% | |
muscle cell | 4 studies | 65% ± 21% | |
brush cell | 4 studies | 44% ± 10% | |
enteroendocrine cell | 4 studies | 26% ± 2% | |
alveolar macrophage | 4 studies | 34% ± 14% | |
myoepithelial cell | 4 studies | 43% ± 23% | |
pancreatic A cell | 3 studies | 45% ± 17% | |
type B pancreatic cell | 3 studies | 48% ± 24% | |
hepatic stellate cell | 3 studies | 51% ± 18% | |
glomerular endothelial cell | 3 studies | 19% ± 0% | |
retinal ganglion cell | 3 studies | 20% ± 2% | |
serous secreting cell | 3 studies | 23% ± 8% | |
endocardial cell | 3 studies | 35% ± 13% | |
retinal rod cell | 3 studies | 22% ± 5% | |
cholangiocyte | 3 studies | 54% ± 13% | |
endothelial cell of sinusoid | 3 studies | 38% ± 16% | |
pancreatic ductal cell | 3 studies | 57% ± 27% | |
ependymal cell | 3 studies | 52% ± 17% | |
adventitial cell | 3 studies | 26% ± 9% | |
type II pneumocyte | 3 studies | 19% ± 2% | |
keratinocyte | 3 studies | 27% ± 10% | |
epithelial cell of proximal tubule | 3 studies | 21% ± 5% | |
renal alpha-intercalated cell | 3 studies | 27% ± 10% | |
mucus secreting cell | 3 studies | 42% ± 13% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 10 studies | 28% ± 11% | |
brain | 9 studies | 25% ± 8% | |
heart | 6 studies | 48% ± 18% | |
eye | 5 studies | 27% ± 16% | |
liver | 4 studies | 34% ± 18% | |
prostate | 4 studies | 35% ± 10% | |
adipose | 4 studies | 32% ± 12% | |
pancreas | 3 studies | 48% ± 21% | |
breast | 3 studies | 29% ± 3% | |
intestine | 3 studies | 18% ± 1% | |
kidney | 3 studies | 25% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 7072.95 | 1439 / 1445 | 100% | 54.22 | 183 / 183 |
prostate | 99% | 13628.91 | 243 / 245 | 100% | 462.72 | 502 / 502 |
breast | 100% | 7369.53 | 458 / 459 | 98% | 61.61 | 1092 / 1118 |
uterus | 100% | 18125.11 | 170 / 170 | 97% | 36.09 | 447 / 459 |
intestine | 99% | 5943.11 | 958 / 966 | 98% | 33.94 | 517 / 527 |
lung | 97% | 5354.08 | 558 / 578 | 98% | 33.50 | 1132 / 1155 |
bladder | 100% | 9371.00 | 21 / 21 | 94% | 26.06 | 472 / 504 |
kidney | 97% | 5291.61 | 86 / 89 | 97% | 39.81 | 874 / 901 |
thymus | 96% | 4252.53 | 630 / 653 | 90% | 23.12 | 544 / 605 |
ovary | 93% | 4869.34 | 168 / 180 | 91% | 19.21 | 392 / 430 |
liver | 92% | 4152.66 | 209 / 226 | 88% | 21.19 | 357 / 406 |
skin | 97% | 5461.00 | 1761 / 1809 | 83% | 19.24 | 391 / 472 |
adrenal gland | 92% | 4080.00 | 237 / 258 | 86% | 29.19 | 198 / 230 |
stomach | 72% | 3355.35 | 259 / 359 | 98% | 38.74 | 279 / 286 |
brain | 65% | 2651.94 | 1719 / 2642 | 98% | 59.17 | 693 / 705 |
pancreas | 55% | 1826.59 | 182 / 328 | 98% | 43.53 | 174 / 178 |
blood vessel | 100% | 20797.56 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 39938.51 | 803 / 803 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 15.34 | 1 / 1 |
adipose | 100% | 7694.73 | 1202 / 1204 | 0% | 0 | 0 / 0 |
heart | 97% | 30440.16 | 831 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 31.25 | 43 / 45 |
spleen | 68% | 2450.89 | 164 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 55% | 8.10 | 16 / 29 |
eye | 0% | 0 | 0 / 0 | 29% | 3.78 | 23 / 80 |
peripheral blood | 13% | 388.71 | 118 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0061049 | Biological process | cell growth involved in cardiac muscle cell development |
GO_0007507 | Biological process | heart development |
GO_0061061 | Biological process | muscle structure development |
GO_0030036 | Biological process | actin cytoskeleton organization |
GO_0061001 | Biological process | regulation of dendritic spine morphogenesis |
GO_0051963 | Biological process | regulation of synapse assembly |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0098793 | Cellular component | presynapse |
GO_0031941 | Cellular component | filamentous actin |
GO_0016020 | Cellular component | membrane |
GO_0030018 | Cellular component | Z disc |
GO_0001725 | Cellular component | stress fiber |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005912 | Cellular component | adherens junction |
GO_0014069 | Cellular component | postsynaptic density |
GO_0042995 | Cellular component | cell projection |
GO_0005080 | Molecular function | protein kinase C binding |
GO_0051371 | Molecular function | muscle alpha-actinin binding |
GO_0098641 | Molecular function | cadherin binding involved in cell-cell adhesion |
GO_0046872 | Molecular function | metal ion binding |
GO_0042805 | Molecular function | actinin binding |
GO_0005515 | Molecular function | protein binding |
GO_0003779 | Molecular function | actin binding |
Gene name | PDLIM5 |
Protein name | PDZ and LIM domain 5 PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein) |
Synonyms | ENH L9 |
Description | FUNCTION: May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Isoforms lacking the LIM domains may negatively modulate the scaffolding activity of isoform 1. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May be required to restrain postsynaptic growth of excitatory synapses. Isoform 1, but not isoform 2, expression favors spine thinning and elongation. . |
Accessions | ENST00000512274.1 ENST00000542407.5 [Q96HC4-4] ENST00000514743.5 [Q96HC4-6] ENST00000627587.2 ENST00000380180.7 [Q96HC4-2] ENST00000359265.8 [Q96HC4-5] ENST00000508216.5 [Q96HC4-2] D6RGG6 ENST00000513341.5 ENST00000317968.9 [Q96HC4-1] ENST00000506632.2 ENST00000509357.5 D6RAA1 ENST00000318007.9 [Q96HC4-3] A0A0D9SFW3 H0YBI4 H0Y8Y3 ENST00000615540.4 [Q96HC4-6] ENST00000510099.5 A0A0A0MSP3 Q96HC4 A0A0D9SFR4 ENST00000437932.5 ENST00000503974.5 [Q96HC4-7] H0Y929 ENST00000504489.3 |