I. Related cell sub types
ID | Name | Number of studies  | |
|---|---|---|---|
| CL_0000057 | fibroblast | 69 | |
| CL_0000632 | hepatic stellate cell | 5 |
ID | Name | Number of studies | |
|---|---|---|---|
| CL_0000057 | fibroblast | 69 | |
| CL_0000632 | hepatic stellate cell | 5 |
Gene | Number of supported studies | Average coverage | Other major groups (express this gene) | Other cell types (express this gene) | |
|---|---|---|---|---|---|
| AGTR1 | 3 | 31% ± 10% | 1 | 2 | |
| NR1H4 | 3 | 49% ± 17% | 1 | 3 | |
| C7 | 3 | 49% ± 8% | 1 | 7 | |
| APOA2 | 3 | 57% ± 33% | 2 | 3 | |
| AHSG | 3 | 44% ± 31% | 2 | 3 | |
| AMBP | 3 | 53% ± 29% | 2 | 3 | |
| FGG | 3 | 62% ± 24% | 2 | 3 | |
| FGA | 3 | 71% ± 20% | 2 | 4 | |
| APOB | 3 | 68% ± 25% | 2 | 5 | |
| FGB | 3 | 70% ± 21% | 2 | 5 | |
| HGF | 3 | 42% ± 2% | 2 | 5 | |
| ADAMTS2 | 3 | 53% ± 11% | 2 | 8 | |
| COL6A3 | 3 | 40% ± 12% | 2 | 9 | |
| STEAP4 | 3 | 21% ± 3% | 2 | 13 | |
| FGL1 | 3 | 56% ± 26% | 3 | 3 | |
| APOC3 | 3 | 65% ± 28% | 3 | 6 | |
| HP | 3 | 66% ± 23% | 3 | 8 | |
| CRISPLD2 | 3 | 41% ± 13% | 3 | 9 | |
| C1R | 3 | 36% ± 16% | 3 | 12 | |
| NID1 | 3 | 44% ± 17% | 3 | 16 | |
| ADAMTS9 | 3 | 38% ± 19% | 3 | 17 | |
| CFH | 3 | 71% ± 9% | 3 | 24 | |
| GATA6 | 3 | 30% ± 11% | 4 | 11 | |
| CCBE1 | 3 | 41% ± 4% | 4 | 11 | |
| BGN | 3 | 22% ± 5% | 4 | 12 | |
| CYP7B1 | 3 | 25% ± 7% | 4 | 12 | |
| CP | 3 | 41% ± 13% | 4 | 16 | |
| COL5A2 | 3 | 37% ± 14% | 4 | 17 | |
| DCN | 3 | 36% ± 2% | 4 | 17 | |
| OSMR | 3 | 35% ± 15% | 4 | 21 |
| GO_0045833 | Biological process | negative regulation of lipid metabolic process |
| GO_0018158 | Biological process | protein oxidation |
| GO_0034382 | Biological process | chylomicron remnant clearance |
| GO_0110024 | Biological process | positive regulation of cardiac muscle myoblast proliferation |
| GO_0010897 | Biological process | negative regulation of triglyceride catabolic process |
| GO_0006642 | Biological process | triglyceride mobilization |
| GO_0002925 | Biological process | positive regulation of humoral immune response mediated by circulating immunoglobulin |
| GO_0072378 | Biological process | blood coagulation, fibrin clot formation |
| GO_0060510 | Biological process | type II pneumocyte differentiation |
| GO_0010886 | Biological process | positive regulation of cholesterol storage |
| GO_0010916 | Biological process | negative regulation of very-low-density lipoprotein particle clearance |
| GO_0032489 | Biological process | regulation of Cdc42 protein signal transduction |
| GO_0060333 | Biological process | type II interferon-mediated signaling pathway |
| GO_0090205 | Biological process | positive regulation of cholesterol metabolic process |
| GO_0008211 | Biological process | glucocorticoid metabolic process |
| GO_0042359 | Biological process | vitamin D metabolic process |
| GO_0034384 | Biological process | high-density lipoprotein particle clearance |
| GO_0042159 | Biological process | lipoprotein catabolic process |
| GO_0034380 | Biological process | high-density lipoprotein particle assembly |
| GO_0034383 | Biological process | low-density lipoprotein particle clearance |
| GO_0042168 | Biological process | heme metabolic process |
| GO_0071377 | Biological process | cellular response to glucagon stimulus |
| GO_0048261 | Biological process | negative regulation of receptor-mediated endocytosis |
| GO_0006706 | Biological process | steroid catabolic process |
| GO_0048012 | Biological process | hepatocyte growth factor receptor signaling pathway |
| GO_0043152 | Biological process | induction of bacterial agglutination |
| GO_0070365 | Biological process | hepatocyte differentiation |
| GO_0002719 | Biological process | negative regulation of cytokine production involved in immune response |
| GO_0051005 | Biological process | negative regulation of lipoprotein lipase activity |
| GO_0031639 | Biological process | plasminogen activation |
| Cell type name | hepatic stellate cell |
| Synonyms | Ito cell hepatic perisinusoidal cell perisinusoidal cell |
| Description | A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver. |
| Parent | CL_0000057 |
