AHSG report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0050766Biological processpositive regulation of phagocytosis
GO_0006953Biological processacute-phase response
GO_0010951Biological processnegative regulation of endopeptidase activity
GO_0030500Biological processregulation of bone mineralization
GO_0046627Biological processnegative regulation of insulin receptor signaling pathway
GO_0050727Biological processregulation of inflammatory response
GO_0006907Biological processpinocytosis
GO_0030502Biological processnegative regulation of bone mineralization
GO_0001501Biological processskeletal system development
GO_0001503Biological processossification
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0070062Cellular componentextracellular exosome
GO_0005794Cellular componentGolgi apparatus
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0031012Cellular componentextracellular matrix
GO_0034774Cellular componentsecretory granule lumen
GO_0072562Cellular componentblood microparticle
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0031093Cellular componentplatelet alpha granule lumen
GO_0004869Molecular functioncysteine-type endopeptidase inhibitor activity
GO_0004866Molecular functionendopeptidase inhibitor activity
GO_0019210Molecular functionkinase inhibitor activity

IV. Literature review

[source]
Gene nameAHSG
Protein nameAlpha-2-HS-glycoprotein (Alpha-2-Z-globulin) (Ba-alpha-2-glycoprotein) (Fetuin-A) [Cleaved into: Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B]
Alpha-2-HS-glycoprotein (Fetuin-A)
SynonymsFETUA
PRO2743
DescriptionFUNCTION: Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.

AccessionsENST00000273784.5
ENST00000411641.7
P02765
C9JV77