COL5A2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001501Biological processskeletal system development
GO_1903225Biological processnegative regulation of endodermal cell differentiation
GO_0030199Biological processcollagen fibril organization
GO_0030198Biological processextracellular matrix organization
GO_0001503Biological processossification
GO_0071230Biological processcellular response to amino acid stimulus
GO_0043588Biological processskin development
GO_0048592Biological processeye morphogenesis
GO_0005615Cellular componentextracellular space
GO_0005592Cellular componentcollagen type XI trimer
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0005576Cellular componentextracellular region
GO_0005588Cellular componentcollagen type V trimer
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0031012Cellular componentextracellular matrix
GO_0030020Molecular functionextracellular matrix structural constituent conferring tensile strength
GO_0046332Molecular functionSMAD binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameCOL5A2
Protein nameCOL5A2 protein
Collagen alpha-2(V) chain
Collagen type V alpha 2 chain
Synonyms
DescriptionFUNCTION: Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue-specific matrices (By similarity). .

FUNCTION: Type I collagen is a member of group I collagen (fibrillar forming collagen). .

FUNCTION: Type I collagen is a member of group I collagen (fibrillar forming collagen). .

AccessionsENST00000374866.9
A0A087WYX9
P05997
Q5PR22
ENST00000618828.1
ENST00000649966.1
A0A3B3IRH9