Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 16 studies | 36% ± 13% | |
club cell | 11 studies | 47% ± 12% | |
epithelial cell | 9 studies | 34% ± 14% | |
fibroblast | 9 studies | 39% ± 21% | |
respiratory goblet cell | 8 studies | 65% ± 13% | |
secretory cell | 8 studies | 44% ± 14% | |
endothelial cell | 8 studies | 39% ± 15% | |
basal cell | 7 studies | 30% ± 15% | |
hepatocyte | 6 studies | 80% ± 16% | |
astrocyte | 6 studies | 31% ± 4% | |
mucus secreting cell | 5 studies | 46% ± 28% | |
Mueller cell | 5 studies | 75% ± 12% | |
deuterosomal cell | 4 studies | 35% ± 8% | |
duct epithelial cell | 4 studies | 61% ± 17% | |
cholangiocyte | 4 studies | 45% ± 31% | |
hepatic stellate cell | 3 studies | 41% ± 13% | |
ependymal cell | 3 studies | 40% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 48208.69 | 226 / 226 | 91% | 237.53 | 368 / 406 |
lung | 59% | 769.92 | 343 / 578 | 63% | 98.19 | 729 / 1155 |
kidney | 57% | 821.74 | 51 / 89 | 50% | 124.95 | 454 / 901 |
breast | 75% | 1063.99 | 342 / 459 | 27% | 39.13 | 304 / 1118 |
bladder | 81% | 713.86 | 17 / 21 | 20% | 20.76 | 100 / 504 |
spleen | 100% | 2120.05 | 240 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 4759.52 | 1319 / 1335 | 0% | 0 | 0 / 0 |
thymus | 96% | 2020.15 | 626 / 653 | 1% | 0.33 | 7 / 605 |
ovary | 4% | 51.25 | 7 / 180 | 89% | 136.69 | 383 / 430 |
adipose | 85% | 1388.65 | 1022 / 1204 | 0% | 0 | 0 / 0 |
intestine | 77% | 1234.40 | 741 / 966 | 7% | 5.52 | 35 / 527 |
prostate | 57% | 893.00 | 140 / 245 | 23% | 8.98 | 117 / 502 |
brain | 51% | 920.71 | 1357 / 2642 | 23% | 13.32 | 163 / 705 |
skin | 60% | 783.58 | 1089 / 1809 | 1% | 0.42 | 6 / 472 |
pancreas | 24% | 623.96 | 80 / 328 | 36% | 26.05 | 64 / 178 |
esophagus | 48% | 424.08 | 689 / 1445 | 9% | 8.04 | 17 / 183 |
heart | 55% | 1734.12 | 473 / 861 | 0% | 0 | 0 / 0 |
uterus | 13% | 164.29 | 22 / 170 | 26% | 34.24 | 121 / 459 |
stomach | 24% | 219.53 | 86 / 359 | 5% | 4.49 | 13 / 286 |
tonsil | 0% | 0 | 0 / 0 | 24% | 21.63 | 11 / 45 |
lymph node | 0% | 0 | 0 / 0 | 21% | 4.77 | 6 / 29 |
muscle | 15% | 113.58 | 120 / 803 | 0% | 0 | 0 / 0 |
adrenal gland | 14% | 93.94 | 36 / 258 | 0% | 0.83 | 1 / 230 |
eye | 0% | 0 | 0 / 0 | 9% | 5.30 | 7 / 80 |
peripheral blood | 1% | 8.26 | 7 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0098869 | Biological process | cellular oxidant detoxification |
GO_0006825 | Biological process | copper ion transport |
GO_0006826 | Biological process | iron ion transport |
GO_0006879 | Biological process | intracellular iron ion homeostasis |
GO_0006878 | Biological process | intracellular copper ion homeostasis |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0072562 | Cellular component | blood microparticle |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0005765 | Cellular component | lysosomal membrane |
GO_0004322 | Molecular function | ferroxidase activity |
GO_0047066 | Molecular function | phospholipid-hydroperoxide glutathione peroxidase activity |
GO_0004602 | Molecular function | glutathione peroxidase activity |
GO_0051087 | Molecular function | protein-folding chaperone binding |
GO_0016491 | Molecular function | oxidoreductase activity |
GO_0016724 | Molecular function | oxidoreductase activity, acting on metal ions, oxygen as acceptor |
GO_0005507 | Molecular function | copper ion binding |
Gene name | CP |
Protein name | CP protein Ceruloplasmin (Cuproxidase ceruloplasmin) (EC 1.16.3.4) (Ferroxidase ceruloplasmin) (EC 1.16.3.1) ferroxidase (EC 1.16.3.1) Ceruloplasmin |
Synonyms | hCG_1781201 |
Description | FUNCTION: Multifunctional blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane . Copper ions provide a large number of enzymatic activites. Oxidizes highly toxic ferrous ions to the ferric state for further incorporation onto apo-transferrins, catalyzes Cu(+) oxidation and promotes the oxidation of biogenic amines such as norepinephrin and serotonin . Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1 (By similarity). Has glutathione peroxidase-like activity, can remove both hydrogen peroxide and lipid hydroperoxide in the presence of thiols . Also shows NO-oxidase and NO2 synthase activities that determine endocrine NO homeostasis . . |
Accessions | ENST00000479771.5 ENST00000494544.1 ENST00000455472.3 ENST00000481169.5 D6RE86 E9PFZ2 H7C5N5 Q6NSB2 P00450 A5PL27 ENST00000264613.11 H7C5R1 |