Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 46 studies | 59% ± 24% | |
pericyte | 21 studies | 35% ± 19% | |
smooth muscle cell | 19 studies | 29% ± 12% | |
connective tissue cell | 17 studies | 50% ± 21% | |
mesothelial cell | 12 studies | 45% ± 21% | |
myofibroblast cell | 9 studies | 47% ± 22% | |
endothelial cell | 8 studies | 27% ± 9% | |
hepatocyte | 5 studies | 63% ± 26% | |
adventitial cell | 5 studies | 77% ± 22% | |
basal cell | 5 studies | 20% ± 5% | |
astrocyte | 4 studies | 24% ± 5% | |
endothelial cell of lymphatic vessel | 3 studies | 35% ± 15% | |
hepatic stellate cell | 3 studies | 36% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 97821.22 | 226 / 226 | 99% | 445.87 | 403 / 406 |
lung | 100% | 35572.65 | 576 / 578 | 97% | 158.20 | 1116 / 1155 |
breast | 99% | 42886.90 | 456 / 459 | 93% | 137.79 | 1036 / 1118 |
ovary | 100% | 63372.33 | 180 / 180 | 90% | 92.11 | 388 / 430 |
uterus | 100% | 37616.64 | 170 / 170 | 90% | 133.78 | 414 / 459 |
prostate | 94% | 24369.56 | 231 / 245 | 92% | 106.99 | 462 / 502 |
bladder | 100% | 47215.24 | 21 / 21 | 82% | 125.11 | 412 / 504 |
intestine | 98% | 26045.92 | 943 / 966 | 80% | 85.10 | 421 / 527 |
esophagus | 91% | 29253.64 | 1315 / 1445 | 78% | 88.71 | 142 / 183 |
skin | 87% | 22828.88 | 1582 / 1809 | 78% | 89.65 | 369 / 472 |
stomach | 73% | 21060.23 | 261 / 359 | 81% | 84.35 | 231 / 286 |
kidney | 75% | 14596.09 | 67 / 89 | 75% | 124.09 | 679 / 901 |
thymus | 98% | 25009.35 | 642 / 653 | 52% | 51.28 | 315 / 605 |
pancreas | 35% | 3383.86 | 115 / 328 | 94% | 243.43 | 167 / 178 |
adrenal gland | 91% | 21198.60 | 234 / 258 | 38% | 37.42 | 87 / 230 |
adipose | 100% | 48885.45 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 112.05 | 29 / 29 |
blood vessel | 100% | 44953.72 | 1333 / 1335 | 0% | 0 | 0 / 0 |
spleen | 98% | 22282.51 | 237 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 125.08 | 43 / 45 |
heart | 83% | 20997.94 | 714 / 861 | 0% | 0 | 0 / 0 |
brain | 2% | 203.97 | 55 / 2642 | 55% | 80.44 | 390 / 705 |
eye | 0% | 0 | 0 / 0 | 23% | 18.61 | 18 / 80 |
muscle | 19% | 1912.17 | 151 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 19.58 | 2 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006955 | Biological process | immune response |
GO_0006958 | Biological process | complement activation, classical pathway |
GO_0045087 | Biological process | innate immune response |
GO_0031638 | Biological process | zymogen activation |
GO_0005615 | Cellular component | extracellular space |
GO_0072562 | Cellular component | blood microparticle |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005576 | Cellular component | extracellular region |
GO_0008236 | Molecular function | serine-type peptidase activity |
GO_0005509 | Molecular function | calcium ion binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0140313 | Molecular function | molecular sequestering activity |
GO_0005515 | Molecular function | protein binding |
GO_0004252 | Molecular function | serine-type endopeptidase activity |
Gene name | C1R |
Protein name | Complement C1r subcomponent (EC 3.4.21.41) (Complement component 1 subcomponent r) [Cleaved into: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain] Complement C1r complement subcomponent C1r (EC 3.4.21.41) |
Synonyms | |
Description | FUNCTION: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. FUNCTION: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. . FUNCTION: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. . FUNCTION: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. . |
Accessions | A0A3B3ISR2 ENST00000647956.2 ENST00000543835.5 F5GWL0 P00736 ENST00000538050.5 F5H3N3 ENST00000541042.5 F5H3A3 ENST00000543362.5 ENST00000540610.5 B4DPQ0 ENST00000535233.6 F5H1V0 ENST00000649804.1 F5H1N6 F5H6Y3 F5H2D0 ENST00000540242.2 A0A3B3ITU4 ENST00000536053.6 |