C1R report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006955Biological processimmune response
GO_0006958Biological processcomplement activation, classical pathway
GO_0045087Biological processinnate immune response
GO_0031638Biological processzymogen activation
GO_0005615Cellular componentextracellular space
GO_0072562Cellular componentblood microparticle
GO_0070062Cellular componentextracellular exosome
GO_0005576Cellular componentextracellular region
GO_0008236Molecular functionserine-type peptidase activity
GO_0005509Molecular functioncalcium ion binding
GO_0042802Molecular functionidentical protein binding
GO_0140313Molecular functionmolecular sequestering activity
GO_0005515Molecular functionprotein binding
GO_0004252Molecular functionserine-type endopeptidase activity

IV. Literature review

[source]
Gene nameC1R
Protein nameComplement C1r subcomponent (EC 3.4.21.41) (Complement component 1 subcomponent r) [Cleaved into: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain]
Complement C1r
complement subcomponent C1r (EC 3.4.21.41)
Synonyms
DescriptionFUNCTION: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.

FUNCTION: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. .

FUNCTION: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. .

FUNCTION: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. .

AccessionsA0A3B3ISR2
ENST00000647956.2
ENST00000543835.5
F5GWL0
P00736
ENST00000538050.5
F5H3N3
ENST00000541042.5
F5H3A3
ENST00000543362.5
ENST00000540610.5
B4DPQ0
ENST00000535233.6
F5H1V0
ENST00000649804.1
F5H1N6
F5H6Y3
F5H2D0
ENST00000540242.2
A0A3B3ITU4
ENST00000536053.6