ADAP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0043087Biological processregulation of GTPase activity
GO_0007507Biological processheart development
GO_0005740Cellular componentmitochondrial envelope
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0043533Molecular functioninositol 1,3,4,5 tetrakisphosphate binding
GO_0005547Molecular functionphosphatidylinositol-3,4,5-trisphosphate binding
GO_0005546Molecular functionphosphatidylinositol-4,5-bisphosphate binding
GO_0030674Molecular functionprotein-macromolecule adaptor activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0005096Molecular functionGTPase activator activity
GO_0043325Molecular functionphosphatidylinositol-3,4-bisphosphate binding

IV. Literature review

[source]
Gene nameADAP2
Protein nameArfGAP with dual PH domains 2
Arf-GAP with dual PH domain-containing protein 2 (Centaurin-alpha-2) (Cnt-a2)
ArfGAP with dual PH domains 2 (Centaurin alpha 2)
SynonymsCENTA2
DescriptionFUNCTION: GTPase-activating protein for the ADP ribosylation factor family (Potential). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). Possesses a stoichiometry of two binding sites for InsP4 with identical affinity. .

AccessionsJ3QLP8
Q9NPF8
ENST00000580526.1
ENST00000581548.5
ENST00000584989.1
Q2V6Q1
ENST00000580525.5
J3QRA6
ENST00000585130.5
J3QRD3
J3KT70
J3KST1
K7ENT1
ENST00000330889.8 [Q9NPF8-1]
ENST00000584828.5
ENST00000581285.5