ZDHHC16 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZDHHC16 at tissue level.

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_0006974Biological processDNA damage response
GO_0018345Biological processprotein palmitoylation
GO_0021537Biological processtelencephalon development
GO_0007507Biological processheart development
GO_0001654Biological processeye development
GO_0005794Cellular componentGolgi apparatus
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0016409Molecular functionpalmitoyltransferase activity
GO_0019706Molecular functionprotein-cysteine S-palmitoyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameZDHHC16
Protein namePalmitoyltransferase ZDHHC16 (EC 2.3.1.225) (Abl-philin 2) (Zinc finger DHHC domain-containing protein 16) (DHHC-16)
Palmitoyltransferase (EC 2.3.1.225)
SynonymsUNQ2570/PRO6258
APH2
DescriptionFUNCTION: Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6 . Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN phosphorylation and homooligomerization (By similarity). Also required for eye development (By similarity). Palmitoylates ZDHHC6, affecting the quaternary assembly of ZDHHC6, its localization, stability and function . May play a role in DNA damage response (By similarity). May be involved in apoptosis regulation (By similarity). Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity). .

AccessionsH0Y6E9
ENST00000417044.1
ENST00000370846.8
ENST00000420089.5
ENST00000370842.6 [Q969W1-2]
B1AMT9
ENST00000433086.5
B1AMU0
ENST00000393760.6 [Q969W1-1]
ENST00000370854.7 [Q969W1-1]
Q969W1
ENST00000345745.9 [Q969W1-4]
B1AMU5
ENST00000414567.5
H0Y536
ENST00000353979.7 [Q969W1-3]
ENST00000352634.8 [Q969W1-2]