Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 3 studies | 27% ± 5% |
Insufficient scRNA-seq data for expression of ZDHHC16 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 1592.48 | 21 / 21 | 100% | 44.44 | 504 / 504 |
breast | 100% | 1342.90 | 459 / 459 | 100% | 53.53 | 1118 / 1118 |
esophagus | 100% | 1394.16 | 1445 / 1445 | 100% | 32.68 | 183 / 183 |
lung | 100% | 2005.00 | 578 / 578 | 100% | 50.52 | 1155 / 1155 |
ovary | 100% | 1477.49 | 180 / 180 | 100% | 41.94 | 430 / 430 |
pancreas | 100% | 1165.85 | 328 / 328 | 100% | 34.65 | 178 / 178 |
prostate | 100% | 1855.38 | 245 / 245 | 100% | 34.14 | 502 / 502 |
stomach | 100% | 1603.23 | 359 / 359 | 100% | 35.29 | 286 / 286 |
thymus | 100% | 1672.30 | 653 / 653 | 100% | 34.63 | 604 / 605 |
intestine | 100% | 1423.20 | 966 / 966 | 100% | 37.40 | 526 / 527 |
uterus | 100% | 1491.44 | 170 / 170 | 100% | 42.18 | 458 / 459 |
kidney | 100% | 1832.57 | 89 / 89 | 100% | 31.73 | 899 / 901 |
liver | 100% | 1354.96 | 226 / 226 | 100% | 27.20 | 405 / 406 |
skin | 100% | 1671.25 | 1808 / 1809 | 100% | 35.51 | 471 / 472 |
brain | 100% | 1229.22 | 2632 / 2642 | 100% | 26.47 | 705 / 705 |
adrenal gland | 100% | 1341.02 | 258 / 258 | 97% | 21.81 | 224 / 230 |
eye | 0% | 0 | 0 / 0 | 100% | 30.36 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 34.63 | 29 / 29 |
muscle | 100% | 1208.02 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1382.88 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 32.04 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 28.77 | 1 / 1 |
adipose | 100% | 1235.06 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1094.46 | 1331 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 1184.88 | 855 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 90% | 818.02 | 836 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006915 | Biological process | apoptotic process |
GO_0006974 | Biological process | DNA damage response |
GO_0018345 | Biological process | protein palmitoylation |
GO_0021537 | Biological process | telencephalon development |
GO_0007507 | Biological process | heart development |
GO_0001654 | Biological process | eye development |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0016409 | Molecular function | palmitoyltransferase activity |
GO_0019706 | Molecular function | protein-cysteine S-palmitoyltransferase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ZDHHC16 |
Protein name | Palmitoyltransferase ZDHHC16 (EC 2.3.1.225) (Abl-philin 2) (Zinc finger DHHC domain-containing protein 16) (DHHC-16) Palmitoyltransferase (EC 2.3.1.225) |
Synonyms | UNQ2570/PRO6258 APH2 |
Description | FUNCTION: Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6 . Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN phosphorylation and homooligomerization (By similarity). Also required for eye development (By similarity). Palmitoylates ZDHHC6, affecting the quaternary assembly of ZDHHC6, its localization, stability and function . May play a role in DNA damage response (By similarity). May be involved in apoptosis regulation (By similarity). Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity). . |
Accessions | H0Y6E9 ENST00000417044.1 ENST00000370846.8 ENST00000420089.5 ENST00000370842.6 [Q969W1-2] B1AMT9 ENST00000433086.5 B1AMU0 ENST00000393760.6 [Q969W1-1] ENST00000370854.7 [Q969W1-1] Q969W1 ENST00000345745.9 [Q969W1-4] B1AMU5 ENST00000414567.5 H0Y536 ENST00000353979.7 [Q969W1-3] ENST00000352634.8 [Q969W1-2] |