Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 6 studies | 30% ± 16% | |
| glutamatergic neuron | 6 studies | 31% ± 15% | |
| GABAergic neuron | 5 studies | 27% ± 9% | |
| astrocyte | 4 studies | 22% ± 10% | |
| epithelial cell | 4 studies | 25% ± 8% | |
| oligodendrocyte precursor cell | 3 studies | 26% ± 13% | |
| microglial cell | 3 studies | 23% ± 8% | |
| neuron | 3 studies | 18% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 7 studies | 24% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2354.60 | 1445 / 1445 | 99% | 21.06 | 182 / 183 |
| stomach | 100% | 1984.04 | 359 / 359 | 99% | 19.41 | 284 / 286 |
| prostate | 100% | 2548.92 | 245 / 245 | 99% | 28.38 | 496 / 502 |
| intestine | 100% | 2637.29 | 966 / 966 | 98% | 17.39 | 519 / 527 |
| thymus | 100% | 3169.96 | 653 / 653 | 98% | 19.59 | 594 / 605 |
| skin | 100% | 2635.70 | 1809 / 1809 | 98% | 19.05 | 463 / 472 |
| lung | 100% | 2638.49 | 578 / 578 | 98% | 16.75 | 1130 / 1155 |
| breast | 100% | 2277.88 | 459 / 459 | 97% | 22.88 | 1089 / 1118 |
| ovary | 100% | 4329.86 | 180 / 180 | 96% | 16.47 | 413 / 430 |
| pancreas | 100% | 1449.73 | 327 / 328 | 96% | 13.01 | 171 / 178 |
| uterus | 100% | 2806.93 | 170 / 170 | 94% | 14.22 | 433 / 459 |
| bladder | 100% | 2441.14 | 21 / 21 | 92% | 12.72 | 465 / 504 |
| kidney | 100% | 1946.01 | 89 / 89 | 90% | 11.76 | 808 / 901 |
| adrenal gland | 100% | 2609.89 | 258 / 258 | 90% | 12.57 | 206 / 230 |
| brain | 95% | 971.16 | 2503 / 2642 | 93% | 11.88 | 657 / 705 |
| liver | 100% | 1226.09 | 226 / 226 | 74% | 7.55 | 299 / 406 |
| adipose | 100% | 2227.34 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 4280.31 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 2705.01 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2008.46 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 16.07 | 45 / 45 |
| heart | 98% | 1712.37 | 841 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 96% | 11.27 | 77 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 19.89 | 27 / 29 |
| peripheral blood | 50% | 825.41 | 464 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0065001 | Biological process | specification of axis polarity |
| GO_0042476 | Biological process | odontogenesis |
| GO_0001835 | Biological process | blastocyst hatching |
| GO_0007507 | Biological process | heart development |
| GO_0070171 | Biological process | negative regulation of tooth mineralization |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0006338 | Biological process | chromatin remodeling |
| GO_0060021 | Biological process | roof of mouth development |
| GO_0030502 | Biological process | negative regulation of bone mineralization |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0140261 | Cellular component | BCOR complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0140297 | Molecular function | DNA-binding transcription factor binding |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0000976 | Molecular function | transcription cis-regulatory region binding |
| GO_0031072 | Molecular function | heat shock protein binding |
| GO_0003714 | Molecular function | transcription corepressor activity |
| GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0042826 | Molecular function | histone deacetylase binding |
| Gene name | BCOR |
| Protein name | BCL-6 corepressor BCL-6 corepressor (BCoR) BCL-6 corepressor (BCOR protein) BCL6 corepressor |
| Synonyms | KIAA1575 |
| Description | FUNCTION: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2). . |
| Accessions | ENST00000615339.2 [Q6W2J9-1] A1A564 ENST00000672922 ENST00000680831.1 [Q6W2J9-1] ENST00000615339 H7BYY2 ENST00000672922.2 [Q6W2J9-1] ENST00000378444.9 [Q6W2J9-1] ENST00000406200.4 [Q6W2J9-1] ENST00000406200 ENST00000342274.8 [Q6W2J9-2] H7BZ37 ENST00000427012.3 H7C231 ENST00000673391.1 [Q6W2J9-2] H7C2V9 ENST00000412952.1 ENST00000413905.6 ENST00000378455.8 [Q6W2J9-4] ENST00000442018.6 C9JHP3 Q6W2J9 A0A5F9ZGX7 ENST00000679513.1 [Q6W2J9-1] ENST00000397354.7 [Q6W2J9-2] |
