I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 21% ± 4% | |
| GABAergic neuron | 3 studies | 30% ± 10% | |
| glutamatergic neuron | 3 studies | 34% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 21% ± 4% | |
| GABAergic neuron | 3 studies | 30% ± 10% | |
| glutamatergic neuron | 3 studies | 34% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 24% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 2858.73 | 245 / 245 | 100% | 19.42 | 502 / 502 |
| thymus | 100% | 1975.92 | 653 / 653 | 100% | 17.26 | 605 / 605 |
| uterus | 100% | 2158.36 | 170 / 170 | 100% | 22.83 | 459 / 459 |
| brain | 100% | 2154.20 | 2638 / 2642 | 100% | 20.05 | 705 / 705 |
| lung | 100% | 2251.54 | 578 / 578 | 100% | 16.02 | 1153 / 1155 |
| bladder | 100% | 2108.52 | 21 / 21 | 100% | 19.44 | 503 / 504 |
| skin | 100% | 2021.03 | 1809 / 1809 | 100% | 21.46 | 471 / 472 |
| stomach | 100% | 1312.47 | 359 / 359 | 100% | 14.47 | 285 / 286 |
| ovary | 100% | 1613.91 | 180 / 180 | 100% | 11.84 | 428 / 430 |
| breast | 100% | 1863.02 | 459 / 459 | 99% | 17.43 | 1112 / 1118 |
| esophagus | 100% | 1793.54 | 1445 / 1445 | 99% | 12.54 | 182 / 183 |
| intestine | 100% | 1863.52 | 966 / 966 | 99% | 15.94 | 524 / 527 |
| adrenal gland | 100% | 2222.02 | 258 / 258 | 99% | 14.28 | 227 / 230 |
| kidney | 100% | 1530.19 | 89 / 89 | 98% | 9.35 | 886 / 901 |
| liver | 100% | 794.15 | 225 / 226 | 96% | 9.12 | 389 / 406 |
| pancreas | 95% | 653.04 | 313 / 328 | 99% | 18.88 | 177 / 178 |
| eye | 0% | 0 | 0 / 0 | 100% | 16.03 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 31.90 | 29 / 29 |
| spleen | 100% | 2952.30 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 19.86 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 17.49 | 1 / 1 |
| adipose | 100% | 1743.70 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1729.92 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 1024.09 | 846 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 1469.58 | 911 / 929 | 0% | 0 | 0 / 0 |
| muscle | 95% | 760.22 | 764 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007420 | Biological process | brain development |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0000184 | Biological process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| GO_0001701 | Biological process | in utero embryonic development |
| GO_0007507 | Biological process | heart development |
| GO_0001654 | Biological process | eye development |
| GO_0005829 | Cellular component | cytosol |
| GO_0005515 | Molecular function | protein binding |
| GO_0042802 | Molecular function | identical protein binding |
| Gene name | SMG9 |
| Protein name | SMG9 nonsense mediated mRNA decay factor Nonsense-mediated mRNA decay factor SMG9 |
| Synonyms | C19orf61 |
| Description | FUNCTION: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons . Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8 . Plays a role in brain, heart, and eye development (By similarity). . |
| Accessions | ENST00000602222.5 M0R2N0 M0QZH1 M0QZC7 ENST00000601170.5 [Q9H0W8-2] M0QYR7 M0QX70 Q9H0W8 ENST00000596714.1 ENST00000601925.5 ENST00000599804.5 ENST00000597586.5 ENST00000270066.11 [Q9H0W8-1] ENST00000597598.1 M0R0U0 |
