Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 3 studies | 27% ± 7% | |
GABAergic neuron | 3 studies | 24% ± 4% | |
glutamatergic neuron | 3 studies | 31% ± 4% | |
astrocyte | 3 studies | 21% ± 6% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 3 studies | 23% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 343.08 | 1439 / 1445 | 100% | 24.98 | 183 / 183 |
ovary | 100% | 467.17 | 180 / 180 | 100% | 9.12 | 428 / 430 |
stomach | 100% | 1433.89 | 358 / 359 | 98% | 23.85 | 281 / 286 |
intestine | 100% | 439.24 | 965 / 966 | 98% | 14.23 | 516 / 527 |
pancreas | 100% | 1433.88 | 328 / 328 | 97% | 10.58 | 172 / 178 |
prostate | 100% | 641.14 | 244 / 245 | 96% | 4.45 | 484 / 502 |
adrenal gland | 100% | 505.15 | 258 / 258 | 95% | 18.48 | 218 / 230 |
liver | 100% | 1121.07 | 226 / 226 | 92% | 6.55 | 372 / 406 |
bladder | 100% | 473.67 | 21 / 21 | 91% | 5.84 | 461 / 504 |
thymus | 100% | 611.28 | 653 / 653 | 91% | 4.64 | 552 / 605 |
brain | 99% | 526.96 | 2627 / 2642 | 90% | 4.01 | 637 / 705 |
skin | 100% | 605.82 | 1807 / 1809 | 89% | 4.87 | 422 / 472 |
uterus | 100% | 489.45 | 170 / 170 | 81% | 3.48 | 371 / 459 |
breast | 100% | 430.32 | 457 / 459 | 80% | 3.82 | 895 / 1118 |
lung | 99% | 460.44 | 575 / 578 | 70% | 6.39 | 808 / 1155 |
kidney | 100% | 429.81 | 89 / 89 | 62% | 2.41 | 563 / 901 |
eye | 0% | 0 | 0 / 0 | 100% | 13.12 | 80 / 80 |
spleen | 100% | 1219.26 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.52 | 1 / 1 |
adipose | 99% | 426.25 | 1191 / 1204 | 0% | 0 | 0 / 0 |
heart | 98% | 484.15 | 840 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 97% | 320.56 | 1297 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 96% | 504.01 | 896 / 929 | 0% | 0 | 0 / 0 |
muscle | 88% | 228.50 | 708 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 83% | 6.25 | 24 / 29 |
tonsil | 0% | 0 | 0 / 0 | 67% | 2.29 | 30 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0060377 | Biological process | negative regulation of mast cell differentiation |
GO_0060319 | Biological process | primitive erythrocyte differentiation |
GO_0003151 | Biological process | outflow tract morphogenesis |
GO_0007507 | Biological process | heart development |
GO_0003192 | Biological process | mitral valve formation |
GO_0003181 | Biological process | atrioventricular valve morphogenesis |
GO_0003195 | Biological process | tricuspid valve formation |
GO_0060413 | Biological process | atrial septum morphogenesis |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0035855 | Biological process | megakaryocyte development |
GO_0055008 | Biological process | cardiac muscle tissue morphogenesis |
GO_0030218 | Biological process | erythrocyte differentiation |
GO_0030851 | Biological process | granulocyte differentiation |
GO_0010724 | Biological process | regulation of definitive erythrocyte differentiation |
GO_0002295 | Biological process | T-helper cell lineage commitment |
GO_0060412 | Biological process | ventricular septum morphogenesis |
GO_0032713 | Biological process | negative regulation of interleukin-4 production |
GO_0060318 | Biological process | definitive erythrocyte differentiation |
GO_0032729 | Biological process | positive regulation of type II interferon production |
GO_0030219 | Biological process | megakaryocyte differentiation |
GO_0032091 | Biological process | negative regulation of protein binding |
GO_0030220 | Biological process | platelet formation |
GO_0035162 | Biological process | embryonic hemopoiesis |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0032642 | Biological process | regulation of chemokine production |
GO_0005654 | Cellular component | nucleoplasm |
GO_0017053 | Cellular component | transcription repressor complex |
GO_0000785 | Cellular component | chromatin |
GO_0005667 | Cellular component | transcription regulator complex |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0003714 | Molecular function | transcription corepressor activity |
GO_0061629 | Molecular function | RNA polymerase II-specific DNA-binding transcription factor binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ZFPM1 |
Protein name | Zinc finger protein, FOG family member 1 Zinc finger protein ZFPM1 (Friend of GATA protein 1) (FOG-1) (Friend of GATA 1) (Zinc finger protein 89A) (Zinc finger protein multitype 1) Zinc finger protein, FOG family member 1 (Zinc finger protein, multitype 1, isoform CRA_b) Zinc finger protein, FOG family member 1 (Zinc finger protein, multitype 1, isoform CRA_c) |
Synonyms | ZFN89A hCG_1811670 FOG1 |
Description | FUNCTION: Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2 (By similarity). . |
Accessions | A0A087WZP1 ENST00000563351.5 ENST00000562437.2 Q8IX07 A0A087X1H8 A0A087WWQ0 ENST00000319555.8 ENST00000569086.5 |