DRC1 | OmnibusX

Name	Number of supported studies	Average coverage
ciliated cell	19 studies	48% ± 15%	Explore
ependymal cell	3 studies	49% ± 9%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of DRC1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	93%	198.88	2453 / 2642	37%	3.34	258 / 705
lung	73%	409.54	424 / 578	40%	2.75	459 / 1155
ovary	9%	5.03	17 / 180	52%	3.22	223 / 430
kidney	30%	15.08	27 / 89	12%	0.69	111 / 901
peripheral blood	42%	19.30	388 / 929	0%	0	0 / 0
adrenal gland	6%	3.64	16 / 258	34%	0.81	79 / 230
uterus	13%	87.14	22 / 170	24%	3.13	111 / 459
thymus	32%	22.13	207 / 653	5%	0.12	32 / 605
prostate	27%	11.57	66 / 245	4%	0.15	22 / 502
breast	19%	6.62	85 / 459	12%	0.41	131 / 1118
intestine	23%	9.08	227 / 966	4%	0.19	22 / 527
pancreas	1%	0.19	2 / 328	25%	1.28	44 / 178
esophagus	10%	3.34	146 / 1445	9%	0.18	17 / 183
spleen	15%	4.78	35 / 241	0%	0	0 / 0
adipose	9%	2.61	108 / 1204	0%	0	0 / 0
bladder	0%	0	0 / 21	9%	0.31	43 / 504
skin	2%	0.83	38 / 1809	3%	0.13	16 / 472
heart	5%	2.05	44 / 861	0%	0	0 / 0
stomach	2%	0.68	7 / 359	2%	0.03	7 / 286
liver	2%	0.68	4 / 226	2%	0.06	9 / 406
muscle	3%	1.16	23 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	2%	0.06	1 / 45
blood vessel	2%	0.62	28 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0003352	Biological process	regulation of cilium movement
GO_0007507	Biological process	heart development
GO_0007368	Biological process	determination of left/right symmetry
GO_0070286	Biological process	axonemal dynein complex assembly
GO_0060285	Biological process	cilium-dependent cell motility
GO_0005930	Cellular component	axoneme
GO_0031514	Cellular component	motile cilium
GO_0005858	Cellular component	axonemal dynein complex
GO_0005829	Cellular component	cytosol
GO_0005515	Molecular function	protein binding

Gene name	DRC1
Protein name	Dynein regulatory complex protein 1 (Coiled-coil domain-containing protein 164) Dynein regulatory complex subunit 1
Synonyms	C2orf39 CCDC164
Description	FUNCTION: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes . Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules . .
Accessions	ENST00000649059.1 F8WE02 A0A3B3IT12 ENST00000421869.5 ENST00000288710.7 Q96MC2

DRC1 report