Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 20 studies | 82% ± 17% | |
| oligodendrocyte | 16 studies | 61% ± 22% | |
| oligodendrocyte precursor cell | 16 studies | 78% ± 21% | |
| glutamatergic neuron | 13 studies | 84% ± 17% | |
| GABAergic neuron | 11 studies | 82% ± 18% | |
| microglial cell | 8 studies | 39% ± 18% | |
| neuron | 7 studies | 62% ± 20% | |
| interneuron | 7 studies | 70% ± 28% | |
| retinal ganglion cell | 7 studies | 67% ± 28% | |
| endothelial cell | 6 studies | 46% ± 21% | |
| amacrine cell | 5 studies | 53% ± 21% | |
| cardiac muscle cell | 5 studies | 36% ± 11% | |
| Mueller cell | 5 studies | 40% ± 12% | |
| type I pneumocyte | 5 studies | 27% ± 6% | |
| granule cell | 4 studies | 79% ± 12% | |
| cholangiocyte | 3 studies | 64% ± 14% | |
| macrophage | 3 studies | 33% ± 10% | |
| differentiation-committed oligodendrocyte precursor | 3 studies | 72% ± 11% | |
| GABAergic interneuron | 3 studies | 80% ± 14% | |
| epithelial cell | 3 studies | 44% ± 10% | |
| glial cell | 3 studies | 46% ± 21% | |
| progenitor cell | 3 studies | 60% ± 28% | |
| GABAergic amacrine cell | 3 studies | 82% ± 13% | |
| OFF-bipolar cell | 3 studies | 74% ± 14% | |
| ON-bipolar cell | 3 studies | 68% ± 12% | |
| glycinergic amacrine cell | 3 studies | 57% ± 13% | |
| retinal pigment epithelial cell | 3 studies | 68% ± 20% | |
| neural progenitor cell | 3 studies | 58% ± 27% | |
| ependymal cell | 3 studies | 71% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 15406.57 | 2642 / 2642 | 100% | 215.07 | 703 / 705 |
| pancreas | 92% | 1982.03 | 302 / 328 | 40% | 3.46 | 71 / 178 |
| prostate | 1% | 17.71 | 3 / 245 | 91% | 9.06 | 458 / 502 |
| adrenal gland | 0% | 5.50 | 1 / 258 | 67% | 14.50 | 153 / 230 |
| breast | 2% | 29.61 | 8 / 459 | 58% | 8.44 | 651 / 1118 |
| liver | 0% | 0 | 0 / 226 | 31% | 7.41 | 127 / 406 |
| eye | 0% | 0 | 0 / 0 | 31% | 2.38 | 25 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 31% | 2.89 | 9 / 29 |
| spleen | 27% | 442.75 | 66 / 241 | 0% | 0 | 0 / 0 |
| ovary | 1% | 7.31 | 1 / 180 | 12% | 1.04 | 51 / 430 |
| heart | 11% | 206.98 | 99 / 861 | 0% | 0 | 0 / 0 |
| lung | 0% | 0 | 0 / 578 | 11% | 1.97 | 128 / 1155 |
| skin | 0% | 6.54 | 8 / 1809 | 7% | 1.10 | 33 / 472 |
| stomach | 0% | 0 | 0 / 359 | 7% | 0.89 | 21 / 286 |
| bladder | 0% | 0 | 0 / 21 | 6% | 1.22 | 29 / 504 |
| uterus | 0% | 0 | 0 / 170 | 6% | 0.54 | 26 / 459 |
| thymus | 0% | 0 | 0 / 653 | 5% | 0.37 | 31 / 605 |
| intestine | 0% | 1.62 | 1 / 966 | 3% | 0.32 | 18 / 527 |
| esophagus | 0% | 0 | 0 / 1445 | 2% | 0.49 | 4 / 183 |
| kidney | 0% | 0 | 0 / 89 | 2% | 0.11 | 16 / 901 |
| blood vessel | 0% | 2.93 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0 | 0 / 1204 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0016055 | Biological process | Wnt signaling pathway |
| GO_0007155 | Biological process | cell adhesion |
| GO_0098609 | Biological process | cell-cell adhesion |
| GO_0050808 | Biological process | synapse organization |
| GO_0060828 | Biological process | regulation of canonical Wnt signaling pathway |
| GO_0060997 | Biological process | dendritic spine morphogenesis |
| GO_0043204 | Cellular component | perikaryon |
| GO_0005912 | Cellular component | adherens junction |
| GO_0030425 | Cellular component | dendrite |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0014069 | Cellular component | postsynaptic density |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0045296 | Molecular function | cadherin binding |
| GO_0008013 | Molecular function | beta-catenin binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CTNND2 |
| Protein name | Catenin delta 2 Catenin delta 2 (cDNA FLJ56233, highly similar to Catenin delta-2) Catenin delta-2 (Delta-catenin) (GT24) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) |
| Synonyms | NPRAP |
| Description | FUNCTION: Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses . Involved in the regulation of Wnt signaling . It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation (By similarity). Functions as a transcriptional activator when bound to ZBTB33 (By similarity). May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules. . |
| Accessions | ENST00000508761.1 D6RF55 D6RBA8 ENST00000513588.5 ENST00000502551.5 A0A994J833 ENST00000511377.5 ENST00000513598.5 ENST00000706271.1 A0A994J5V2 E9PHB5 B4DRK2 D6RC65 A0A994J5I1 Q9UQB3 D6RHE9 ENST00000504499.5 E7EPC8 ENST00000706272.1 ENST00000304623.13 [Q9UQB3-1] ENST00000503622.5 ENST00000511278.5 |