Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 11 studies | 19% ± 5% | |
type I pneumocyte | 7 studies | 27% ± 5% | |
endothelial cell | 7 studies | 24% ± 7% | |
ciliated cell | 6 studies | 25% ± 8% | |
CD16-positive, CD56-dim natural killer cell, human | 4 studies | 18% ± 2% | |
epithelial cell | 4 studies | 28% ± 5% | |
GABAergic neuron | 4 studies | 41% ± 10% | |
astrocyte | 4 studies | 20% ± 4% | |
oligodendrocyte precursor cell | 4 studies | 28% ± 5% | |
interneuron | 4 studies | 34% ± 20% | |
oligodendrocyte | 4 studies | 19% ± 2% | |
smooth muscle cell | 3 studies | 17% ± 1% | |
CD16-negative, CD56-bright natural killer cell, human | 3 studies | 18% ± 3% | |
capillary endothelial cell | 3 studies | 16% ± 1% | |
plasma cell | 3 studies | 17% ± 1% | |
glutamatergic neuron | 3 studies | 55% ± 8% | |
adipocyte | 3 studies | 22% ± 4% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 40% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 15987.67 | 180 / 180 | 100% | 28.64 | 430 / 430 |
prostate | 100% | 13705.06 | 245 / 245 | 100% | 41.16 | 501 / 502 |
thymus | 100% | 14508.82 | 653 / 653 | 100% | 53.66 | 603 / 605 |
breast | 100% | 17553.53 | 459 / 459 | 99% | 31.53 | 1112 / 1118 |
kidney | 100% | 8617.78 | 89 / 89 | 99% | 36.24 | 892 / 901 |
lung | 100% | 15203.36 | 578 / 578 | 99% | 24.57 | 1143 / 1155 |
bladder | 100% | 16082.38 | 21 / 21 | 99% | 22.92 | 498 / 504 |
skin | 99% | 18889.56 | 1794 / 1809 | 99% | 26.33 | 469 / 472 |
intestine | 100% | 17056.62 | 966 / 966 | 98% | 21.97 | 519 / 527 |
pancreas | 99% | 8455.33 | 326 / 328 | 99% | 33.93 | 176 / 178 |
stomach | 100% | 13740.07 | 359 / 359 | 98% | 20.94 | 280 / 286 |
esophagus | 100% | 18265.59 | 1444 / 1445 | 98% | 19.11 | 179 / 183 |
uterus | 99% | 15894.16 | 169 / 170 | 97% | 24.09 | 445 / 459 |
adrenal gland | 98% | 9609.01 | 254 / 258 | 98% | 32.94 | 225 / 230 |
brain | 94% | 9435.04 | 2496 / 2642 | 100% | 50.73 | 704 / 705 |
liver | 77% | 3481.58 | 173 / 226 | 93% | 15.90 | 376 / 406 |
adipose | 100% | 17518.34 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 22967.23 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 29.23 | 80 / 80 |
spleen | 100% | 12999.08 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 21.92 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.00 | 1 / 1 |
muscle | 100% | 17575.77 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 97% | 10295.03 | 834 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 93% | 16.82 | 27 / 29 |
peripheral blood | 87% | 5363.83 | 810 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030518 | Biological process | nuclear receptor-mediated steroid hormone signaling pathway |
GO_0007165 | Biological process | signal transduction |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0016055 | Biological process | Wnt signaling pathway |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0005829 | Cellular component | cytosol |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0043565 | Molecular function | sequence-specific DNA binding |
GO_0003682 | Molecular function | chromatin binding |
GO_0000976 | Molecular function | transcription cis-regulatory region binding |
GO_0008013 | Molecular function | beta-catenin binding |
GO_0003712 | Molecular function | transcription coregulator activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0003713 | Molecular function | transcription coactivator activity |
GO_0030374 | Molecular function | nuclear receptor coactivator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | CALCOCO1 |
Protein name | Calcium-binding and coiled-coil domain-containing protein 1 Calcium-binding and coiled-coil domain-containing protein 1 (Calphoglin) (Coiled-coil coactivator protein) (Sarcoma antigen NY-SAR-3) Calcium binding and coiled-coil domain 1 Alternative protein CALCOCO1 |
Synonyms | PP13275 UNQ2436/PRO4996 KIAA1536 |
Description | FUNCTION: Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions (By similarity). In association with CCAR1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells . .; FUNCTION: Seems to enhance inorganic pyrophosphatase thus activating phosphogluomutase (PMG). Probably functions as a component of the calphoglin complex, which is involved in linking cellular metabolism (phosphate and glucose metabolism) with other core functions including protein synthesis and degradation, calcium signaling and cell growth. . |
Accessions | F8VZI3 ENST00000552623.5 F8VRQ9 F8VXS2 F8W0X2 H3BRW8 F8VQE3 F8VWP8 ENST00000549688.1 ENST00000549349.5 ENST00000550804.6 [Q9P1Z2-1] ENST00000546443.5 ENST00000546619.5 F8VPN1 ENST00000430117.6 [Q9P1Z2-4] ENST00000549784.5 ENST00000548177.5 Q9P1Z2 F8VUB3 ENST00000548263.5 [Q9P1Z2-2] ENST00000262059.8 [Q9P1Z2-3] ENST00000551900.5 L8ECJ1 ENST00000549173.5 |