Name | Number of supported studies | Average coverage | |
---|---|---|---|
classical monocyte | 12 studies | 25% ± 12% | |
B cell | 7 studies | 19% ± 3% | |
monocyte | 6 studies | 19% ± 3% | |
memory B cell | 6 studies | 18% ± 3% | |
microglial cell | 6 studies | 23% ± 6% | |
macrophage | 6 studies | 20% ± 3% | |
epithelial cell | 5 studies | 28% ± 12% | |
neutrophil | 4 studies | 20% ± 4% | |
non-classical monocyte | 4 studies | 27% ± 12% | |
myeloid cell | 4 studies | 24% ± 9% | |
basal cell | 4 studies | 23% ± 3% | |
conventional dendritic cell | 3 studies | 25% ± 8% | |
ciliated cell | 3 studies | 20% ± 2% | |
glutamatergic neuron | 3 studies | 18% ± 1% | |
plasmacytoid dendritic cell | 3 studies | 18% ± 2% | |
astrocyte | 3 studies | 26% ± 7% | |
oligodendrocyte precursor cell | 3 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4689.11 | 1445 / 1445 | 100% | 28.79 | 183 / 183 |
prostate | 100% | 6869.88 | 245 / 245 | 100% | 42.05 | 502 / 502 |
breast | 100% | 4460.42 | 459 / 459 | 100% | 44.08 | 1116 / 1118 |
thymus | 100% | 4057.87 | 653 / 653 | 100% | 26.27 | 602 / 605 |
uterus | 100% | 3289.79 | 170 / 170 | 99% | 24.66 | 456 / 459 |
skin | 100% | 6399.53 | 1809 / 1809 | 99% | 20.82 | 467 / 472 |
intestine | 100% | 5315.62 | 966 / 966 | 99% | 19.22 | 521 / 527 |
lung | 100% | 5279.80 | 577 / 578 | 99% | 24.39 | 1143 / 1155 |
stomach | 100% | 3242.38 | 359 / 359 | 99% | 19.94 | 282 / 286 |
bladder | 100% | 2603.95 | 21 / 21 | 97% | 19.68 | 491 / 504 |
kidney | 100% | 3325.35 | 89 / 89 | 97% | 16.92 | 871 / 901 |
ovary | 100% | 3678.93 | 180 / 180 | 95% | 17.33 | 410 / 430 |
brain | 91% | 1585.72 | 2394 / 2642 | 99% | 25.20 | 701 / 705 |
pancreas | 76% | 1066.67 | 249 / 328 | 96% | 17.52 | 171 / 178 |
adrenal gland | 97% | 1634.75 | 251 / 258 | 73% | 10.91 | 168 / 230 |
liver | 71% | 1744.05 | 161 / 226 | 56% | 6.05 | 226 / 406 |
adipose | 100% | 4151.33 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3457.70 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 21.17 | 29 / 29 |
peripheral blood | 100% | 14156.56 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 6542.97 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 27.03 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 14.44 | 1 / 1 |
eye | 0% | 0 | 0 / 0 | 99% | 13.25 | 79 / 80 |
heart | 72% | 1255.28 | 623 / 861 | 0% | 0 | 0 / 0 |
muscle | 61% | 1014.18 | 486 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0016055 | Biological process | Wnt signaling pathway |
GO_0120163 | Biological process | negative regulation of cold-induced thermogenesis |
GO_0009887 | Biological process | animal organ morphogenesis |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
GO_1990907 | Cellular component | beta-catenin-TCF complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005667 | Cellular component | transcription regulator complex |
GO_0005634 | Cellular component | nucleus |
GO_0003714 | Molecular function | transcription corepressor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | TLE3 |
Protein name | Transducin-like enhancer of split 3 splice variant 1 TLE family member 3, transcriptional corepressor TLE family member 3, transcriptional corepressor (Transducin-like enhancer of split 3 short isoform) Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3) Transducin-like enhancer of split 3 splice variant 2 |
Synonyms | KIAA1547 |
Description | FUNCTION: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity). . |
Accessions | Q6PRX2 ENST00000560525.6 H0YKN8 ENST00000559048.5 [Q04726-4] H0YKH0 Q6PRX3 ENST00000557919.5 H0YNT2 ENST00000537387.2 H0YLI3 ENST00000559191.5 ENST00000558201.5 ENST00000559929.5 ENST00000557907.5 [Q04726-3] H0YLW9 ENST00000557997.5 [Q04726-3] H0YNI7 Q04726 H0YL70 ENST00000558379.5 [Q04726-6] ENST00000451782.7 [Q04726-5] H0YKH5 ENST00000558939.5 [Q04726-1] ENST00000560939.5 ENST00000557984.6 Q672R2 ENST00000440567.7 [Q04726-7] ENST00000317509.12 [Q04726-2] ENST00000560589.5 H0YKT5 ENST00000561453.5 |