DLX3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DLX3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DLX3 at tissue level.

III. Associated gene sets

GO_0042475Biological processodontogenesis of dentin-containing tooth
GO_0009790Biological processembryo development
GO_0030855Biological processepithelial cell differentiation
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0031069Biological processhair follicle morphogenesis
GO_0035315Biological processhair cell differentiation
GO_0001890Biological processplacenta development
GO_0030509Biological processBMP signaling pathway
GO_0071895Biological processodontoblast differentiation
GO_0001568Biological processblood vessel development
GO_0071335Biological processhair follicle cell proliferation
GO_0010467Biological processgene expression
GO_0016055Biological processWnt signaling pathway
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005737Cellular componentcytoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003682Molecular functionchromatin binding
GO_0000976Molecular functiontranscription cis-regulatory region binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDLX3
Protein nameHomeobox protein DLX-3
Distal-less homeobox 3
Synonyms
DescriptionFUNCTION: Transcriptional activator (By similarity). Activates transcription of GNRHR, via binding to the downstream activin regulatory element (DARE) in the gene promoter (By similarity). .

AccessionsO60479
ENST00000434704.2
ENST00000512495.2
F8VXG1