I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 21% ± 6% | |
| basal cell | 3 studies | 27% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 21% ± 6% | |
| basal cell | 3 studies | 27% ± 7% |
Insufficient scRNA-seq data for expression of WNT7B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 84% | 850.65 | 207 / 245 | 90% | 18.03 | 452 / 502 |
| brain | 85% | 569.67 | 2258 / 2642 | 64% | 15.73 | 451 / 705 |
| lung | 57% | 326.16 | 332 / 578 | 83% | 39.54 | 958 / 1155 |
| bladder | 48% | 918.38 | 10 / 21 | 70% | 37.84 | 355 / 504 |
| breast | 35% | 136.13 | 162 / 459 | 75% | 16.36 | 833 / 1118 |
| esophagus | 39% | 759.47 | 557 / 1445 | 70% | 45.84 | 128 / 183 |
| ureter | 0% | 0 | 0 / 0 | 100% | 124.77 | 1 / 1 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 40.26 | 43 / 45 |
| pancreas | 3% | 8.30 | 10 / 328 | 80% | 18.02 | 143 / 178 |
| uterus | 4% | 29.80 | 6 / 170 | 78% | 29.51 | 356 / 459 |
| skin | 71% | 2049.72 | 1287 / 1809 | 5% | 1.94 | 24 / 472 |
| ovary | 0% | 0 | 0 / 180 | 47% | 6.45 | 201 / 430 |
| thymus | 7% | 20.11 | 46 / 653 | 20% | 1.92 | 122 / 605 |
| kidney | 15% | 242.74 | 13 / 89 | 8% | 1.52 | 74 / 901 |
| intestine | 0% | 0.41 | 1 / 966 | 14% | 3.40 | 76 / 527 |
| stomach | 0% | 0.91 | 1 / 359 | 13% | 2.33 | 36 / 286 |
| liver | 1% | 1.97 | 2 / 226 | 11% | 3.11 | 46 / 406 |
| peripheral blood | 2% | 8.36 | 20 / 929 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 258 | 2% | 0.24 | 4 / 230 |
| blood vessel | 0% | 1.87 | 4 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 0% | 1.38 | 3 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.76 | 2 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_0036516 | Biological process | chemoattraction of dopaminergic neuron axon |
| GO_0071300 | Biological process | cellular response to retinoic acid |
| GO_0060535 | Biological process | trachea cartilage morphogenesis |
| GO_0030324 | Biological process | lung development |
| GO_0048568 | Biological process | embryonic organ development |
| GO_0060560 | Biological process | developmental growth involved in morphogenesis |
| GO_0001701 | Biological process | in utero embryonic development |
| GO_0022009 | Biological process | central nervous system vasculogenesis |
| GO_0021871 | Biological process | forebrain regionalization |
| GO_0072205 | Biological process | metanephric collecting duct development |
| GO_0032536 | Biological process | regulation of cell projection size |
| GO_0046330 | Biological process | positive regulation of JNK cascade |
| GO_0060669 | Biological process | embryonic placenta morphogenesis |
| GO_0060710 | Biological process | chorio-allantoic fusion |
| GO_0072053 | Biological process | renal inner medulla development |
| GO_0072054 | Biological process | renal outer medulla development |
| GO_0045669 | Biological process | positive regulation of osteoblast differentiation |
| GO_0003338 | Biological process | metanephros morphogenesis |
| GO_0072207 | Biological process | metanephric epithelium development |
| GO_0060070 | Biological process | canonical Wnt signaling pathway |
| GO_0072061 | Biological process | inner medullary collecting duct development |
| GO_0070307 | Biological process | lens fiber cell development |
| GO_0072060 | Biological process | outer medullary collecting duct development |
| GO_0030182 | Biological process | neuron differentiation |
| GO_0061180 | Biological process | mammary gland epithelium development |
| GO_0051384 | Biological process | response to glucocorticoid |
| GO_0045165 | Biological process | cell fate commitment |
| GO_0060425 | Biological process | lung morphogenesis |
| GO_0060482 | Biological process | lobar bronchus development |
| GO_0072236 | Biological process | metanephric loop of Henle development |
| GO_0048144 | Biological process | fibroblast proliferation |
| GO_0016332 | Biological process | establishment or maintenance of polarity of embryonic epithelium |
| GO_0060428 | Biological process | lung epithelium development |
| GO_0042592 | Biological process | homeostatic process |
| GO_0032364 | Biological process | intracellular oxygen homeostasis |
| GO_0060071 | Biological process | Wnt signaling pathway, planar cell polarity pathway |
| GO_0016055 | Biological process | Wnt signaling pathway |
| GO_0050808 | Biological process | synapse organization |
| GO_0072089 | Biological process | stem cell proliferation |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030666 | Cellular component | endocytic vesicle membrane |
| GO_0005796 | Cellular component | Golgi lumen |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0048018 | Molecular function | receptor ligand activity |
| GO_0005109 | Molecular function | frizzled binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0005125 | Molecular function | cytokine activity |
| Gene name | WNT7B |
| Protein name | Protein Wnt Protein Wnt-7b |
| Synonyms | |
| Description | FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway . Required for normal fusion of the chorion and the allantois during placenta development (By similarity). Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation . . FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. . FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. . FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. . FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. . |
| Accessions | B8A595 ENST00000410089.5 A8K0G1 ENST00000410058.1 ENST00000339464.9 ENST00000428540.1 B8A597 ENST00000409496.7 P56706 B8A598 |
